ALDH4A1

Gene Symbol	ALDH4A1
Entrez Gene	8659
Alt Symbol	ALDH4, P5CD, P5CDh
Species	Human
Gene Type	protein-coding
Description	aldehyde dehydrogenase 4 family, member A1
Other Description	L-glutamate gamma-semialdehyde dehydrogenase|P5C dehydrogenase|aldehyde dehydrogenase family 4 member A1|delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial|mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase
Swissprots	Q16882 A8K1Q7 Q53HU4 Q96IF0 Q9UDI6 Q8IZ38 P30038 D2D4A3 Q5JNV6 B4DGE4
Accessions	EAW94858 EAW94859 EAW94860 P30038 AK222486 BAD96206 AK289972 BAF82661 AK294552 BAG57755 BC007581 AAH07581 BC023600 AAH23600 BM856369 BX649081 DC318624 DQ893505 ABM84431 DQ896489 ABM87488 FJ462711 ACN89883 U24266 AAC50500 U24267 AAC50501 XM_011542352 XP_011540654 XM_011542353 XP_011540655 XR_946786 NM_001161504 NP_001154976 NM_003748 NP_003739 NM_170726 NP_733844
Function	Irreversible conversion of delta-1-pyrroline-5- carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. {ECO:0000269|PubMed:22516612}.
Subcellular Location	Mitochondrion matrix.
Tissue Specificity	Highest expression is found in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas.
Top Pathways	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ALDH4A1 full length protein - ab160138 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

P5CDH / ALDH4A1 Antibody Blocking Peptide - LS-E16685 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P5CDH / ALDH4A1 Antibody Blocking Peptide - LS-E16686 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P5CDH / ALDH4A1 Antibody Blocking Peptide - LS-E9336 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

P5CDH / ALDH4A1 Antibody Blocking Peptide - LS-E9337 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ALDH4A1 Protein - H00008659-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ALDH4A1-Antibody-Center-Blocking-Peptide - BP7875c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ALDH4A1-Antibody-C-term-Blocking-Peptide - BP7875b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human ALDH4A1 protein - orb138152 from Biorbyt Category Protein Prices $417.00, $859.00 Sizes 20 μg, 100 μg Source Baculovirus-Insect Cells Species Human

Human ALDH4A1 protein (GST Tag) - orb138151 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Baculovirus-Insect Cells Species Human

Aldh4a1 Blocking Peptide - 33R-3562 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ALDH4A1 Blocking Peptide - 33R-7563 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ALDH4A1 Blocking Peptide - 33R-8071 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ALDH4 - H00008659-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ALDH4 - H00008659-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ALDH4A1 fusion protein - ag2147 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Aldehyde Dehydrogenase 4 Family, Member A1, GST-tagged - ALDH4A1-499H from Creative Biomart Category Protein

Recombinant Human ALDH4A1, Gly & Pro tagged - ALDH4A1-516H from Creative Biomart Category Protein Source Baculovirus-Insect cells Species Human

Recombinant Human Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial(A - CSB-YP001576HU CSB-EP001576HU CSB-BP001576HU CSB-MP001576HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ALDH4 (transcript variant P5CDhS) - TP304884 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ALDH4 (transcript variant P5CDhL) - TP320893 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human ALDH4A1 Protein, His & GST-tagged - ALDH4A1-472H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

ALDH4A1 Recombinant Protein Antigen - NBP1-89149PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

ALDH4A1-Blocking-Peptide-C-term - BP20738c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ALDH4A1 Peptide, Human - M34GP00487H from Creative Peptides Category Peptide Source Synthetic. Species Human

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