RMI1

Gene Symbol RMI1
Entrez Gene 80010
Alt Symbol BLAP75, C9orf76, FAAP75
Species Human
Gene Type protein-coding
Description RecQ mediated genome instability 1
Other Description BLM-associated polypeptide, 75 kDa|BLM-associated protein 75 kDa|RMI1, RecQ mediated genome instability 1, homolog|homolog of yeast RecQ-mediated genome instability 1 (RMI1)|recQ-mediated genome instability protein 1
Swissprots Q9H9A7 Q5SQG8 Q05CW3 Q6P1Q4 Q7Z6L6 Q05BX1 Q6PI89 Q5SQG9
Accessions EAW62682 EAW62683 Q9H9A7 AJ420435 AK022950 BAB14325 BC020606 AAH20606 BC032494 AAH32494 BC039999 AAH39999 BC044571 BC053549 AAH53549 BC064937 AAH64937 BP327553 DN997105 XM_005252211 XP_005252268 XM_005252213 XP_005252270 XM_011519034 XP_011517336 NM_024945 NP_079221
Function Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability. {ECO:0000269|PubMed:15775963, ECO:0000269|PubMed:16537486, ECO:0000269|PubMed:16595695}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15775963}. Note=Forms foci in response to DNA damage.
Top Pathways Fanconi anemia pathway

C9orf76 293T Cell Transient Overexpression Lysate(Denatured) - H00080010-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

RMI1 293T Cell Transient Overexpression Lysate(Denatured) - H00080010-T02 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

RMI1 overexpression lysate - LY410898 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

RMI1 293 Cell Lysate - 405521 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

BLAP75 Overexpression Lysate (Denatured) - H00080010-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
Lane 1: C9orf76 transfected lysate (41.8 KDa). Lane 2: Non-transfected lysate.

RMI1 Over-expression Lysate Product - GWB-28B18E from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

BLAP75 Overexpression Lysate (Denatured) - H00080010-T02 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human RMI1 Knockdown Stable Cell Line - CSC-DC013337 from Creative biogene

Category Cell Line
Species Human
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