RMI1

Gene Symbol	RMI1
Entrez Gene	80010
Alt Symbol	BLAP75, C9orf76, FAAP75
Species	Human
Gene Type	protein-coding
Description	RecQ mediated genome instability 1
Other Description	BLM-associated polypeptide, 75 kDa|BLM-associated protein 75 kDa|RMI1, RecQ mediated genome instability 1, homolog|homolog of yeast RecQ-mediated genome instability 1 (RMI1)|recQ-mediated genome instability protein 1
Swissprots	Q9H9A7 Q5SQG8 Q05CW3 Q6P1Q4 Q7Z6L6 Q05BX1 Q6PI89 Q5SQG9
Accessions	EAW62682 EAW62683 Q9H9A7 AJ420435 AK022950 BAB14325 BC020606 AAH20606 BC032494 AAH32494 BC039999 AAH39999 BC044571 BC053549 AAH53549 BC064937 AAH64937 BP327553 DN997105 XM_005252211 XP_005252268 XM_005252213 XP_005252270 XM_011519034 XP_011517336 NM_024945 NP_079221
Function	Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability. {ECO:0000269|PubMed:15775963, ECO:0000269|PubMed:16537486, ECO:0000269|PubMed:16595695}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15775963}. Note=Forms foci in response to DNA damage.
Top Pathways	Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BLAP75 full length protein - ab153518 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BLAP75 / RMI1 Antibody Blocking Peptide - LS-E4535 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BLAP75 / RMI1 Antibody Blocking Peptide - LS-E16896 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human BLAP75 Protein - H00080010-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RMI1-Antibody-N-term-Blocking-Peptide - BP16875a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RMI1 Blocking Peptide - 33R-1953 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RMI1 / BLAP75 - H00080010-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RMI1 / BLAP75 - H00080010-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RMI1 fusion protein - Ag6208 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

RMI1 fusion protein - Ag6301 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human RMI1, GST-tagged - RMI1-2319H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human RecQ-mediated genome instability protein 1(RMI1) - CSB-YP875699HU CSB-EP875699HU CSB-BP875699HU CSB-MP875699HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RMI1 / BLAP75 - TP308030 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

BLAP75 Protein - NBP2-47541PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

BLAP75 Protein - NBP2-47540PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

RMI1 Peptide, Human - M34GP13337H from Creative Peptides Category Peptide Source Synthetic. Species Human

RecQ-mediated genome instability protein 1 (RMI1), Recombinant Protein - MBS1346244 from MyBioSource Category Protein Prices $1,420.00, $1,420.00, $1,650.00, $1,650.00, $2,400.00, $2,400.00, $2,845.00, $2,845.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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