RMI1

Gene Symbol RMI1
Entrez Gene 80010
Alt Symbol BLAP75, C9orf76, FAAP75
Species Human
Gene Type protein-coding
Description RecQ mediated genome instability 1
Other Description BLM-associated polypeptide, 75 kDa|BLM-associated protein 75 kDa|RMI1, RecQ mediated genome instability 1, homolog|homolog of yeast RecQ-mediated genome instability 1 (RMI1)|recQ-mediated genome instability protein 1
Swissprots Q9H9A7 Q5SQG8 Q05CW3 Q6P1Q4 Q7Z6L6 Q05BX1 Q6PI89 Q5SQG9
Accessions EAW62682 EAW62683 Q9H9A7 AJ420435 AK022950 BAB14325 BC020606 AAH20606 BC032494 AAH32494 BC039999 AAH39999 BC044571 BC053549 AAH53549 BC064937 AAH64937 BP327553 DN997105 XM_005252211 XP_005252268 XM_005252213 XP_005252270 XM_011519034 XP_011517336 NM_024945 NP_079221
Function Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability. {ECO:0000269|PubMed:15775963, ECO:0000269|PubMed:16537486, ECO:0000269|PubMed:16595695}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15775963}. Note=Forms foci in response to DNA damage.
Top Pathways Fanconi anemia pathway

RMI1 CRISPR/Cas9 KO Plasmid (h) - sc-413321 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RMI1 HDR Plasmid (h) - sc-413321-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RMI1 Double Nickase Plasmid (h) - sc-413321-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RMI1 Double Nickase Plasmid (h2) - sc-413321-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RMI1 CRISPR Activation Plasmid (h) - sc-413321-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RMI1 CRISPR Activation Plasmid (h2) - sc-413321-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RMI1 Lentiviral Activation Particles (h) - sc-413321-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RMI1 Lentiviral Activation Particles (h2) - sc-413321-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RMI1 siRNA (h) - sc-72651 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RMI1 shRNA Plasmid (h) - sc-72651-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RMI1 shRNA (h) Lentiviral Particles - sc-72651-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BLAP75 RNAi - H00080010-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU133211 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18311 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18311 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08823 from Sigma-Aldrich

Category miRNA

RMI1 siRNA (Human) - CRJ2722 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RMI1 - MBS8214817 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RMI1 (NM_024945.2) - SHH396173 from Creative biogene

Category siRNA
Species Reactivities Human

Human RMI1 siRNA - orb273223 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RMI1 shRNA Plasmid (Human) - CHJ2722 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RMI1 miRNA 3'UTR clone - MiUTR1H-08846 from Creative biogene

Species Reactivities Human
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