RMI1

Gene Symbol	RMI1
Entrez Gene	80010
Alt Symbol	BLAP75, C9orf76, FAAP75
Species	Human
Gene Type	protein-coding
Description	RecQ mediated genome instability 1
Other Description	BLM-associated polypeptide, 75 kDa\|BLM-associated protein 75 kDa\|RMI1, RecQ mediated genome instability 1, homolog\|homolog of yeast RecQ-mediated genome instability 1 (RMI1)\|recQ-mediated genome instability protein 1
Swissprots	Q9H9A7 Q5SQG8 Q05CW3 Q6P1Q4 Q7Z6L6 Q05BX1 Q6PI89 Q5SQG9
Accessions	EAW62682 EAW62683 Q9H9A7 AJ420435 AK022950 BAB14325 BC020606 AAH20606 BC032494 AAH32494 BC039999 AAH39999 BC044571 BC053549 AAH53549 BC064937 AAH64937 BP327553 DN997105 XM_005252211 XP_005252268 XM_005252213 XP_005252270 XM_011519034 XP_011517336 NM_024945 NP_079221
Function	Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability. {ECO:0000269\|PubMed:15775963, ECO:0000269\|PubMed:16537486, ECO:0000269\|PubMed:16595695}.
Subcellular Location	Nucleus {ECO:0000269\|PubMed:15775963}. Note=Forms foci in response to DNA damage.
Top Pathways	Fanconi anemia pathway

RMI1 (C-20) - sc-79872 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

RMI1 (H-89) - sc-368686 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

RMI1 (N-16) - sc-79874 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

RMI1 (G-20) - sc-79873 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-BLAP75 antibody - ab70525 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling BLAP75 with ab70525 at 1/200 (1µg/ml). Detection: DAB.

Anti-BLAP75 antibody - ab87223 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BLAP75 antibody (ab87223) at 1 µg/ml (5% skim milk / PBS buffer) + Transfected 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-BLAP75 antibody - ab130643 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BLAP75 antibody (ab130643) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

Anti-BLAP75 antibody - ab84387 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

ab84387, at 1/250 dilution, staining BLAP75 in formalin fixed, paraffin embedded human skin basal cell carcinoma tissue by Immunohistochemistry. Detection: DAB staining using anti-Rabbit IHC antibody at a dilution of 1/100.

Anti-BLAP75 antibody [EPR12157(B)] - ab172625 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR12157(B)

Immunofluorescent analysis of HeLa cells labeling BLAP75 with ab172625 at 1/50 dilution.

Anti-BLAP75 / RMI1 Antibody (aa275-300) - LS-C286358 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human BLAP75 by Immunohistochemistry. Sample: FFPE section of human skin basal cell carcinoma. Antibody: Affinity purified rabbit anti-BLAP75 used at a dilution of 1:250. Detection: DAB staining using anti-Rabbit IHC antibody at a dilution of 1:100.

Anti-BLAP75 / RMI1 Antibody (aa275-300) - LS-C287503 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human BLAP75 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-BLAP75 used at a dilution of 1:200 (1 ug/ml).

Anti-BLAP75 / RMI1 Antibody (aa275-300) - LS-C77068 from LifeSpan Bioscience

Prices	$545.00
Sizes	20 µg
Host	Rabbit
Clonality	Polyclonal

Anti-BLAP75 / RMI1 Antibody (aa105-133, AP) - LS-C227018 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BLAP75 / RMI1 Antibody (aa105-133, APC) - LS-C227019 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BLAP75 / RMI1 Antibody (aa105-133, Biotin) - LS-C227020 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BLAP75 / RMI1 Antibody (aa105-133, FITC) - LS-C227021 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BLAP75 / RMI1 Antibody (aa105-133, PE) - LS-C227024 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BLAP75 / RMI1 Antibody (aa105-133, Azide-free, HRP) - LS-C227022 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BLAP75 / RMI1 Antibody (aa104-133) - LS-C324699 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-BLAP75 / RMI1 Antibody (aa71-120) - LS-C102220 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

RMI1 / BLAP75 antibody LS-C102220 Western blot of Transfected 293T cell lysate.

Anti-BLAP75 / RMI1 Antibody (aa105-133) - LS-C162634 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

RMI1 Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The RMI1 antibody detected the RMI1 protein (arrow).

BLAP75 Antibody - NB100-1720 from Novus Biologicals

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: BLAP75 Antibody [NB100-1720] - Samples: Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-BLAP75 antibody NB100-1720 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate (B).

BLAP75 Antibody - NBP1-58133 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: BLAP75 Antibody [NBP1-58133] - Transfected 293T cell lysate, concentration 0.2-1 ug/ml.

BLAP75 Antibody - H00080010-B02P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: BLAP75 Antibody [H00080010-B02P] - Analysis of RMI1 expression in transfected 293T cell line by RMI1 polyclonal antibody. Lane 1: C9orf76 transfected lysate(51.7 KDa). Lane 2: Non-transfected lysate.

BLAP75 Antibody - H00080010-B01 from Novus Biologicals

Prices	$349.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: BLAP75 Antibody [H00080010-B01] - analysis of C9orf76 expression in transfected 293T cell line by C9orf76 MaxPab polyclonal antibody (B01). Lane 1: C9orf76 transfected lysate (41.80 KDa). Lane 2: Non-transfected lysate.

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