Fadd

Gene Symbol Fadd
Entrez Gene 14082
Alt Symbol Mort1/FADD
Species Mouse
Gene Type protein-coding
Description Fas (TNFRSF6)-associated via death domain
Other Description FAS-associated death domain protein|FAS-associating death domain-containing protein|Fas-associating protein with death domain|mediator of receptor induced toxicity|protein FADD
Swissprots Q3TC37 Q61082 Q61160
Accessions EDL18257 Q61160 AK007648 AK031396 BAC27384 AK084808 BAC39283 AK169798 BAE41374 AK170927 BAE42120 AK179010 AK198513 BC004584 AAH04584 BC021400 AAH21400 U43184 AAA97876 U50406 AAB07789 NM_010175 NP_034305
Function Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity). {ECO:0000250}.
Top Pathways Chagas disease (American trypanosomiasis), TNF signaling pathway, Herpes simplex infection, Tuberculosis, Apoptosis

Phospho-FADD (Ser191) Antibody (Mouse Specific) - 2785 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

FADD (F-12) - sc-166516 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FADD (F-12): sc-166516. Western blot analysis of FADD expression in non-transfected: sc-117752 (A) and mouse FADD transfected: sc-126821 (B) 293T whole cell lysates.

FADD (M-19) - sc-6036 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FADD (M-19): sc-6036. Western blot analysis of FADD expression in NIH/3T3 whole cell lysate (A) and mouse embryo (B) and lung (C) tissue extracts.

Anti-FADD antibody [EPR5030] - ab124812 from Abcam

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5030
All lanes : Anti-FADD antibody [EPR5030] (ab124812) at 1/1000 dilutionLane 1 : Mouse spleen lysateLane 2 : Raw264.7 cell lysateLane 3 : NIH/3T3 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

FADD Antibody (EP887Y) - NB110-56985 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP887Y
Western Blot: FADD Antibody (EP887Y) [NB110-56985] Jurkat cell lysates.

FADD Polyclonal Antibody - bs-0511R from Bioss

Prices $279.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
L1 mouse liver lysates, L2 mouse brain lysates probed with Anti FADD Polyclonal Antibody, Unconjugated (bs-0511R) at 1:200 in 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in 37˚C. Predicted band and observed band size: 23kD

FADD (Ser191) Polyclonal Antibody - bs-3135R from Bioss

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-FADD Polyclonal Antibody, Cy3 Conjugated - bs-0511R-Cy3 from Bioss

Host Rabbit
Clonality Polyclonal

Rabbit Anti-FADD Polyclonal Antibody, Cy5 Conjugated - bs-0511R-Cy5 from Bioss

Host Rabbit
Clonality Polyclonal

Rabbit Anti-FADD Polyclonal Antibody, Cy7 Conjugated - bs-0511R-Cy7 from Bioss

Host Rabbit
Clonality Polyclonal

Rabbit Anti-FADD Polyclonal Antibody, FITC Conjugated - bs-0511R-FITC from Bioss

Host Rabbit
Clonality Polyclonal

FADD Polyclonal Antibody, Biotin Conjugated - bs-0511R-Biotin from Bioss

Prices $359.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FADD Polyclonal Antibody, HRP Conjugated - bs-0511R-HRP from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ANTI-MOUSE PHOSPHO-FADD-S191 antibody produced in rabbit - SAB1303559 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-phospho-FADD (pSer191) antibody produced in rabbit - SAB4301377 from Sigma-Aldrich

Prices $310.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-phospho-FADD (pSer<SUP>191</SUP>): <B>Cat. No. SAB4301377</B>: Immunohistochemical analysis of paraffin-embedded Human breast carcinoma tissue using FADD (Phospho-Ser191) antibody

Anti-FADD (AB2) antibody produced in rabbit - AV30294 from Sigma-Aldrich

Prices $347.50, $347.50
Sizes 50 µg, 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: SP2/0 (<B>Cat. No. AV30294</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 0.25 μg/mL in cell type SP2/0

FADD antibody - C-terminal region (ARP30294_P050) - ARP30294_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Phospho-mouse-FADDS191-Antibody - AP3103a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of anti-mFADD Pab (Cat. #AP3103a) in mouse heart tissue lysate.mFADD(arrow) was detected using the purified Pab.

FADD-Antibody-Phospho-pS194 - AJ1284b from Abgent, a WuXi AppTec company

Host Rabbit
Clonality Monoclonal
Clone EPR1816Y
A. Western blot analysis on Jurkat cell lysates using anti-phosho FADD (pS194) RabMAb (Cat. #AJ1284b), 1:500 dilution. Cells were either (A) untreated (B) treated with calyculin A

FADD-Antibody-N-term - AJ1284a from Abgent, a WuXi AppTec company

Host Rabbit
Clonality Monoclonal
Clone EP887Y
A. Western blot analysis on Jurkat cell lysates using anti-FADD RabMAb (Cat. #AJ1284a), 1:500 dilution.
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