| Gene Symbol | Fadd |
|---|---|
| Entrez Gene | 14082 |
| Alt Symbol | Mort1/FADD |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | Fas (TNFRSF6)-associated via death domain |
| Other Description | FAS-associated death domain protein|FAS-associating death domain-containing protein|Fas-associating protein with death domain|mediator of receptor induced toxicity|protein FADD |
| Swissprots | Q3TC37 Q61082 Q61160 |
| Accessions | EDL18257 Q61160 AK007648 AK031396 BAC27384 AK084808 BAC39283 AK169798 BAE41374 AK170927 BAE42120 AK179010 AK198513 BC004584 AAH04584 BC021400 AAH21400 U43184 AAA97876 U50406 AAB07789 NM_010175 NP_034305 |
| Function | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity). {ECO:0000250}. |
| Top Pathways | Chagas disease (American trypanosomiasis), TNF signaling pathway, Herpes simplex infection, Tuberculosis, Apoptosis |
Protein FADD (FADD), Mouse, ELISA Kit - CSB-EL007958MO from ARP American Research Products
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FADD (Phospho-Ser191) Colorimetric Cell-Based ELISA Kit - CBP1858 from Assay Biotechnology
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Fas (TNFRSF6) -associated via death domain, ELISA Kit - MBS927150 from MyBioSource
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Mouse Protein FADD(FADD) ELISA kit - CSB-EL007958MO from Cusabio
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FADD (Phospho-Ser191) ELISA Kit - DEIA-XYA637 from Creative Diagnostics
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Mouse Protein FADD (FADD) ELISA Kit - EKC37660 from Biomatik
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Mouse Fadd ELISA Kit - E052694 from Biobool
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FADD ELISA Kit (Mouse) (OKCA01749) - OKCA01749 from Aviva Systems Biology
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