EIF3A

Gene Symbol	EIF3A
Entrez Gene	8661
Alt Symbol	EIF3, EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 3, subunit A
Other Description	EIF3, p180 subunit|centrosomin homolog|cytoplasmic protein p167|eIF-3-theta|eIF3 p167|eIF3 p180|eIF3 p185|eukaryotic translation initiation factor 3 subunit 10|eukaryotic translation initiation factor 3 subunit A|eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD)|eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD)|eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa|eukaryotic translation initiation factor 3, subunit 10, 170kD
Swissprots	Q15778 F5H335 Q14152 O00653 B1AMV5 B4DYS1
Accessions	AAB41586 EAW49408 Q14152 AJ227915 AK302575 BAG63833 AK307610 AK309542 AU279600 BC020285 BC033769 AAH33769 BC054342 AAH54342 BC064926 AAH64926 BC107776 AAI07777 BC114429 AAI14430 D50929 BAA09488 JX312508 AFR31791 U58046 AAB41584 U78311 AAB80695 NM_003750 NP_003741
Function	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. {ECO:0000255|HAMAP- Rule:MF_03000, ECO:0000269|PubMed:11169732}.
Subcellular Location	Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03000, ECO:0000269|PubMed:9150439}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EIF3A overexpression lysate - LY401232 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

EIF3A 293 Cell Lysate - 401135 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

EIF3A Overexpression Lysate (Native) - NBL1-10188 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

EIF3A Over-expression Lysate Product - GWB-DC20D1 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

Panoply™ Human EIF3A Knockdown Stable Cell Line - CSC-DC004810 from Creative biogene Category Cell Line Species Human

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