EIF3A

Gene Symbol	EIF3A
Entrez Gene	8661
Alt Symbol	EIF3, EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 3, subunit A
Other Description	EIF3, p180 subunit|centrosomin homolog|cytoplasmic protein p167|eIF-3-theta|eIF3 p167|eIF3 p180|eIF3 p185|eukaryotic translation initiation factor 3 subunit 10|eukaryotic translation initiation factor 3 subunit A|eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD)|eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD)|eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa|eukaryotic translation initiation factor 3, subunit 10, 170kD
Swissprots	Q15778 F5H335 Q14152 O00653 B1AMV5 B4DYS1
Accessions	AAB41586 EAW49408 Q14152 AJ227915 AK302575 BAG63833 AK307610 AK309542 AU279600 BC020285 BC033769 AAH33769 BC054342 AAH54342 BC064926 AAH64926 BC107776 AAI07777 BC114429 AAI14430 D50929 BAA09488 JX312508 AFR31791 U58046 AAB41584 U78311 AAB80695 NM_003750 NP_003741
Function	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. {ECO:0000255|HAMAP- Rule:MF_03000, ECO:0000269|PubMed:11169732}.
Subcellular Location	Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03000, ECO:0000269|PubMed:9150439}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

eIF3A (D51F4) XP ® Rabbit mAb - 3411 from Cell Signaling Technology Prices $109.00, $277.00 Sizes 20 µl (2 western blots), 100 µl (10 western blots) Host Rabbit Clonality Monoclonal Clone D51F4

eIF3A Antibody - 2538 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

eIF3θ (E-1) - sc-365789 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

eIF3θ (H-300) - sc-30149 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

eIF3θ (L-18) - sc-22375 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-eIF3A antibody - ab86146 from Abcam Prices $380.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-eIF3A antibody - ab105113 from Abcam Prices $410.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-eIF3A antibody - ab118357 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-eIF3A antibody [EPR5819(2)] - ab128996 from Abcam Prices $313.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR5819(2)

Anti-EIF3A Antibody - LS-C65766 from LifeSpan Bioscience Prices $405.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-EIF3A Antibody (clone 2G4) - LS-C139256 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2G4

Anti-EIF3A Antibody - LS-C190068 from LifeSpan Bioscience Prices $445.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EIF3A Antibody (clone 2G11) - LS-C194712 from LifeSpan Bioscience Prices $590.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2G11

Anti-EIF3A Antibody (aa1218-1247, APC) - LS-C256571 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EIF3A / EIF3 Antibody (C-Terminus) - LS-C145469 from LifeSpan Bioscience Host Rabbit Clonality Polyclonal

Anti-EIF3A Antibody (aa1218-1247, AP) - LS-C256572 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EIF3A Antibody (aa1218-1247, Biotin) - LS-C256573 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EIF3A Antibody (aa1218-1247, FITC) - LS-C256574 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EIF3A Antibody (aa1218-1247, Azide-free, HRP) - LS-C256575 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EIF3A Antibody (aa1218-1247, PE) - LS-C256577 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EIF3A Antibody (aa1218-1247) - LS-C329493 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EIF3A Antibody (aa1-50) - LS-C288761 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-EIF3A Antibody (aa550-600) IHC-plus™ - LS-B7957 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-EIF3A Antibody (aa622-848) - LS-C293794 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EIF3A Antibody (aa860-910) - LS-C288760 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Search more