WT1

Gene Symbol	WT1
Entrez Gene	7490
Alt Symbol	AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33
Species	Human
Gene Type	protein-coding
Description	Wilms tumor 1
Other Description	Wilms tumor protein\|amino-terminal domain of EWS\|last three zinc fingers of the DNA-binding domain of WT1
Swissprots	Q4VXV4 Q16575 Q16256 Q15881 A8K6S1 Q4VXV6 Q4VXV5 Q8IYZ5 B3KSA5 P19544
Accessions	AAA61299 AAA62865 AAB19895 AAB20109 AAB20110 AAB20111 AAB20112 AAC60604 AAC60605 AAD14879 AAO61088 AAR06172 ABK15552 ABK15553 AGX31264 AHH02461 BAF85820 CAA43819 CAA51057 CAA51062 EAW68220 EAW68221 EAW68222 EAW68223 EAW68224 EAW68225 EAW68226 P19544 AK093168 BAG52667 AK291736 BAF84425 BC032861 AAH32861 BC046461 AAH46461 BG718348 JF432657 ADZ15874 M30393 AAA36810 S74529 AAB33427 S75264 AAB33443 X51630 CAA35956 NM_000378 NP_000369 NM_001198551 NP_001185480 NM_001198552 NP_001185481 NM_024424 NP_077742 NM_024426 NP_077744 NM_024425
Function	Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. {ECO:0000269\|PubMed:19123921, ECO:0000269\|PubMed:19416806}.
Subcellular Location	Isoform 4: Nucleus, nucleoplasm.
Tissue Specificity	Expressed in the kidney and a subset of hematopoietic cells.
Top Pathways	Transcriptional misregulation in cancer

Human-WT1-cDNA-Clone - DC06533 from Abgent, a WuXi AppTec company

Prices	$225.00
Sizes	10 µg
Species	Human
Accession	BC032861

WT1 - MBS1278202 from MyBioSource

Species	Human
Accession	BC032861

Human WT1 ORF Clone(NM_001198551.1) - CDCR358872 from Creative Biomart

Species	Human
Accession	NM_001198551.1

Human WT1 ORF Clone(NM_001198551.1) - CDCR358873 from Creative Biomart

Species	Human
Accession	NM_001198551.1

Human WT1 ORF Clone(NM_001198552.1) - CDCR358874 from Creative Biomart

Species	Human
Accession	NM_001198552.1

Human WT1 ORF Clone(NM_001198552.1) - CDCR358875 from Creative Biomart

Species	Human
Accession	NM_001198552.1

human WT1 ORF clone - CDCH101568 from Creative Biomart

Species	Human
Accession	NM_000378

human WT1 ORF clone - CDCH101569 from Creative Biomart

Species	Human
Accession	NM_000378

human WT1 ORF clone - CDCH101570 from Creative Biomart

Species	Human
Accession	NM_000378

human WT1 ORF clone - CDCH101571 from Creative Biomart

Species	Human
Accession	NM_000378

human WT1 ORF clone - CDCH101572 from Creative Biomart

Species	Human
Accession	NM_000378

human WT1 ORF clone - CDCH101573 from Creative Biomart

Species	Human
Accession	NM_000378

human WT1 ORF clone - CDCH101574 from Creative Biomart

Species	Human
Accession	NM_000378

human WT1 ORF clone - CDCH101575 from Creative Biomart

Species	Human
Accession	NM_000378

human WT1 ORF clone - CDCH101576 from Creative Biomart

Species	Human
Accession	NM_000378

human WT1 ORF clone - CDCH101577 from Creative Biomart

Species	Human
Accession	NM_000378

human WT1 ORF clone - CDCH101578 from Creative Biomart

Species	Human
Accession	NM_000378

human WT1 ORF clone - CDCH101579 from Creative Biomart

Species	Human
Accession	NM_000378

Human WT1 ORF Clone(NM_000378.4) - CDCL181374 from Creative Biomart

Species	Human
Accession	NM_000378.4

Human WT1 Gene ORF cDNA clone in cloning vector - HG12282-G from Sino Biological

Species	Human

Human WT1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12282-ACR from Sino Biological

Species	Human

Human WT1 Gene ORF cDNA clone expression plasmid - HG12282-UT from Sino Biological

Species	Human

Human WT1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG12282-ANR from Sino Biological

Species	Human

Human WT1 Gene ORF cDNA clone expression plasmid, C-His tag - HG12282-CH from Sino Biological

Species	Human

Human WT1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12282-ACG from Sino Biological

Species	Human

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