HIRA

Gene Symbol	HIRA
Entrez Gene	7290
Alt Symbol	DGCR1, TUP1, TUPLE1
Species	Human
Gene Type	protein-coding
Description	histone cell cycle regulator
Other Description	DiGeorge critical region gene 1|HIR histone cell cycle regulation defective homolog A|TUP1-like enhancer of split protein 1|protein HIRA
Swissprots	Q05BU9 Q8IXN2 P54198
Accessions	CAA62800 EAX03043 EAX03044 P54198 AK289809 BAF82498 AK299950 BAG61778 AK302835 BAH13816 AK308642 BC032721 AAH32721 BC039835 AAH39835 CR456503 CAG30389 CU013101 CAK54532 CU013389 CAK54831 X75296 CAA53044 X77633 CAA54721 X81844 CAA57436 X89887 CAA61979 NM_003325 NP_003316
Function	Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. {ECO:0000269|PubMed:12370293, ECO:0000269|PubMed:14718166, ECO:0000269|PubMed:15621527}.
Subcellular Location	Nucleus. Nucleus, PML body. Note=Primarily, though not exclusively, localized to the nucleus. Localizes to PML bodies immediately prior to onset of senescence.
Tissue Specificity	Expressed at high levels in kidney, pancreas and skeletal muscle and at lower levels in brain, heart, liver, lung, and placenta. {ECO:0000269|PubMed:9063745}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HIRA full length protein - ab152773 from Abcam Category Protein Source Wheat germ Species Human

Human HIRA peptide - ab22456 from Abcam Category Peptide

Human HIRA protein fragment - ab152774 from Abcam Category Protein Source Wheat germ Species Human

HIRA Antibody Blocking Peptide - LS-E4645 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HIRA Antibody Blocking Peptide - LS-E8172 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HIRA Antibody Blocking Peptide - LS-E13293 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HIRA Recombinant Protein - H00007290-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human HIRA Protein - H00007290-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HIRA Peptide - P1888 from Novus Biologicals Category Peptide Species Human

HIRA-Antibody-N-term-Blocking-Peptide - BP17007a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HIRA-Antibody-Center-Blocking-Peptide - BP6277c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HIRA / TUPLE1 - H00007290-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

HIRA / TUPLE1 - H00007290-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

HIRA / TUPLE1 - H00007290-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Recombinant Human Protein HIRA(HIRA) ,partial - CSB-YP010371HU CSB-EP010371HU CSB-BP010371HU CSB-MP010371HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HIRA Protein - abx163238 from Abbexa Category Protein Species Human

HIRA Recombinant Protein Antigen - NBP2-38636PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HIRA Peptide, Human - M34GP07005H from Creative Peptides Category Peptide Source Synthetic. Species Human

HIRA Recombinant Protein Antigen - NBP2-55647PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Protein HIRA (HIRA), partial, Recombinant Protein - MBS968354 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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