NR1D2

Gene Symbol NR1D2
Entrez Gene 9975
Alt Symbol BD73, EAR-1R, RVR
Species Human
Gene Type protein-coding
Description nuclear receptor subfamily 1, group D, member 2
Other Description V-erbA-related protein 1-related|nuclear receptor Rev-ErbA beta variant 1|nuclear receptor Rev-ErbA beta variant 2|nuclear receptor subfamily 1 group D member 2|orphan nuclear hormone receptor BD73|rev-erb alpha-related receptor|rev-erb-beta|rev-erba-alpha-related receptor
Swissprots Q86XD4 Q14995 B2R8Q3 O00402
Accessions EAW64340 EAW64341 Q14995 AB209091 BAD92328 AB307693 BAH02284 AK293273 BAG56802 AK301925 BAG63345 AK313464 BAG36250 BC015929 AAH15929 BC045613 AAH45613 BC070035 AAH70035 BX537786 CA312643 CA412377 CR457434 CAG33715 D16815 BAA20088 DR004486 HQ692830 ADZ17341 HQ692831 ADZ17342 L31785 AAA65937 XM_006713451 XP_006713514 NM_001145425 NP_001138897 NM_005126 NP_005117 NR_110524
Function Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the expression of core clock components ARNTL/BMAL1 and CLOCK. Also regulates genes involved in metabolic functions, including lipid metabolism and the inflammatory response. Acts as a receptor for heme which stimulates its interaction with the NCOR1/HDAC3 corepressor complex, enhancing transcriptional repression. Recognizes two classes of DNA response elements within the promoter of its target genes and can bind to DNA as either monomers or homodimers, depending on the nature of the response element. Binds as a monomer to a response element composed of the consensus half-site motif 5'-[A/G]GGTCA-3' preceded by an A/T-rich 5' sequence (RevRE), or as a homodimer to a direct repeat of the core motif spaced
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:17892483, ECO:0000269|PubMed:17996965}.
Tissue Specificity Widely expressed. Expressed at high levels in the liver, adipose tissue, skeletal muscle and brain. Expression oscillates diurnally in the suprachiasmatic nucleus (SCN) of the hypothalamus as well as in peripheral tissues.

Rat NR1D2 ELISA Kit (Sandwich ELISA) - LS-F6923 from LifeSpan Bioscience

Category ELISA Kit
Prices $780.00
Sizes 1 plate
Sensitivity 0.066 ng/ml
Range 0.156-10 ng/ml

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS056836 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS092678 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS074022 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS069423 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS074290 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS062792 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS081486 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS076630 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS052836 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS097664 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS080532 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS069528 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS085913 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

nuclear receptor subfamily 1, group D, member 2, ELISA Kit - MBS9329833 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS107202 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS065992 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS100052 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS104929 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS081635 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS076277 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS102136 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2, ELISA Kit - MBS106489 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2), ELISA Kit - MBS2024445 from MyBioSource

Category ELISA Kit
Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.066ng/mL.
Range 0.156-10ng/mL

ELISA Kit for Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2) - SED946Ra from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.066ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL
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