PDCD1LG2

Gene Symbol	PDCD1LG2
Entrez Gene	80380
Alt Symbol	B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2
Species	Human
Gene Type	protein-coding
Description	programmed cell death 1 ligand 2
Other Description	B7 dendritic cell molecule|B7-DC|PD-1 ligand 2|PD-1-ligand 2|PDCD1 ligand 2|butyrophilin B7-DC|programmed death ligand 2
Swissprots	Q5T7Z6 Q6JXL8 Q9BQ51 Q6JXL9 Q14CN8
Accessions	EAW58762 Q9BQ51 AF329193 AAK31105 AF344424 AAK15370 AK001872 AY254343 AAP13471 AY271901 AAP49000 AY271902 AAP49001 BC074766 AAH74766 BC113678 AAI13679 BC113680 AAI13681 BC143920 BC143921 BX951459 CA442083 DQ336699 ABC59616 EF444806 ABO33153 HQ258142 ADR82896 XM_005251600 XP_005251657 NM_025239 NP_079515
Function	Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). {ECO:0000250}.
Subcellular Location	Isoform 1: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. {ECO:0000269|PubMed:11224527}.
Top Pathways	Cell adhesion molecules (CAMs)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PDCD1LG2-Over-expression-Lysate - LY16180a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

PDCD1LG2 overexpression lysate - LY410802 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PD-L2/B7-DC/PDCD1LG2 Overexpression Lysate (Native) - NBP2-06213 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Human B7-DC / PD-L2 / CD273 / PDCD1LG2 HEK293 Cell Lysate (WB positive control) - 10292-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Cynomolgus B7-DC / PD-L2 / CD273 HEK293 Cell Lysate (WB positive control) - 90249-C08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Cynomolgus B7-DC / PD-L2 / CD273 HEK293 Cell Lysate (WB positive control) - 90249-C02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Human B7-DC / PD-L2 / CD273 HEK293 Cell Lysate (WB positive control) - 10292-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human B7-DC / PD-L2 / CD273 HEK293 Cell Lysate (WB positive control) - 10292-H03HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human PD-L2 Human Cells Transfected Lysate (positive control) (denatured) - orb173126 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Human B7-DC Human Cells Transfected Lysate (positive control) (denatured) - orb232815 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human PD-L2 Human Cells Transfected Lysate (positive control) (denatured) - orb172988 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human PDCD1LG2 Knockdown Stable Cell Line - CSC-DC011482 from Creative biogene Category Cell Line Species Human

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