PDCD1LG2

Gene Symbol PDCD1LG2
Entrez Gene 80380
Alt Symbol B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2
Species Human
Gene Type protein-coding
Description programmed cell death 1 ligand 2
Other Description B7 dendritic cell molecule|B7-DC|PD-1 ligand 2|PD-1-ligand 2|PDCD1 ligand 2|butyrophilin B7-DC|programmed death ligand 2
Swissprots Q5T7Z6 Q6JXL8 Q9BQ51 Q6JXL9 Q14CN8
Accessions EAW58762 Q9BQ51 AF329193 AAK31105 AF344424 AAK15370 AK001872 AY254343 AAP13471 AY271901 AAP49000 AY271902 AAP49001 BC074766 AAH74766 BC113678 AAI13679 BC113680 AAI13681 BC143920 BC143921 BX951459 CA442083 DQ336699 ABC59616 EF444806 ABO33153 HQ258142 ADR82896 XM_005251600 XP_005251657 NM_025239 NP_079515
Function Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). {ECO:0000250}.
Subcellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. {ECO:0000269|PubMed:11224527}.
Top Pathways Cell adhesion molecules (CAMs)

Pdcd-1L2 CRISPR/Cas9 KO Plasmid (h) - sc-404344 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1L2 HDR Plasmid (h) - sc-404344-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1L2 Double Nickase Plasmid (h) - sc-404344-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1L2 Double Nickase Plasmid (h2) - sc-404344-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1L2 CRISPR Activation Plasmid (h) - sc-404344-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1L2 CRISPR Activation Plasmid (h2) - sc-404344-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1L2 Lentiviral Activation Particles (h) - sc-404344-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1L2 Lentiviral Activation Particles (h2) - sc-404344-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pdcd-1L2 siRNA (h) - sc-39701 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pdcd-1L2 shRNA Plasmid (h) - sc-39701-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pdcd-1L2 shRNA (h) Lentiviral Particles - sc-39701-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU017821 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16516 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16516 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PDCD1LG2 siRNA (Human) - CRJ2877 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PDCD1LG2 (NM_025239.3) - SHH372176 from Creative biogene

Category siRNA
Species Reactivities Human

Human PDCD1LG2 siRNA - orb273378 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PDCD1LG2 shRNA Plasmid (Human) - CHJ2877 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PDCD1LG2 miRNA 3'UTR clone - MiUTR3H-07911 from Creative biogene

Species Reactivities Human
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