PDCD1LG2

Gene Symbol	PDCD1LG2
Entrez Gene	80380
Alt Symbol	B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2
Species	Human
Gene Type	protein-coding
Description	programmed cell death 1 ligand 2
Other Description	B7 dendritic cell molecule|B7-DC|PD-1 ligand 2|PD-1-ligand 2|PDCD1 ligand 2|butyrophilin B7-DC|programmed death ligand 2
Swissprots	Q5T7Z6 Q6JXL8 Q9BQ51 Q6JXL9 Q14CN8
Accessions	EAW58762 Q9BQ51 AF329193 AAK31105 AF344424 AAK15370 AK001872 AY254343 AAP13471 AY271901 AAP49000 AY271902 AAP49001 BC074766 AAH74766 BC113678 AAI13679 BC113680 AAI13681 BC143920 BC143921 BX951459 CA442083 DQ336699 ABC59616 EF444806 ABO33153 HQ258142 ADR82896 XM_005251600 XP_005251657 NM_025239 NP_079515
Function	Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). {ECO:0000250}.
Subcellular Location	Isoform 1: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. {ECO:0000269|PubMed:11224527}.
Top Pathways	Cell adhesion molecules (CAMs)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-PDCD1LG2-cDNA-Clone - DC09874 from Abgent, a WuXi AppTec company Prices $368.55 Sizes 10 µg Species Human Accession BC113678

Human PD-L2/B7-DC (NP_079515) VersaClone cDNA - RDC1133 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

Mouse PD-L2/B7-DC (NP_067371) VersaClone cDNA - RDC1183 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

PDCD1LG2 - MBS1273797 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC113678

Human PD-L2/B7-DC/CD273 Gene ORF cDNA clone in cloning vector - HG10292-G from Sino Biological Species Human

Human PD-L2/B7-DC/CD273 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10292-ACG from Sino Biological Species Human

Human PD-L2/B7-DC/CD273 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10292-ACR from Sino Biological Species Human

Human PD-L2/B7-DC/CD273 Gene ORF cDNA clone expression plasmid, N-His tag - HG10292-NH from Sino Biological Species Human

Human PDCD1LG2 / PD-L2 natural ORF mammalian expression plasmid - HG10292-UT from Sino Biological Species Human Accession NM_025239.3

Human PD-L2/B7-DC/CD273 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10292-CY from Sino Biological Species Human

Human PD-L2/B7-DC/CD273 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10292-NF from Sino Biological Species Human

Human PD-L2/B7-DC/CD273 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10292-CF from Sino Biological Species Human

Human PD-L2/B7-DC/CD273 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10292-NM from Sino Biological Species Human

Human PD-L2/B7-DC/CD273 Gene ORF cDNA clone expression plasmid, C-His tag - HG10292-CH from Sino Biological Species Human

Human PD-L2/B7-DC/CD273 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10292-NY from Sino Biological Species Human

Human PD-L2/B7-DC/CD273 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10292-CM from Sino Biological Species Human

Cynomolgus Monkey PD-L2/B7-DC (XP_005581839) VersaClone cDNA - RDC1291 from R&D Systems Prices $199.00 Sizes 10 µg Species Monkey

Human PD-L2 ORF clone(NM_025239.3) - CDCL185684 from Creative biogene Species Human

Human PDCD1LG2 ORF Clone (BC113678) - CDCS415943 from Creative biogene Species Human Accession Q9BQ51

Human PD-L2 Gene cDNA Clone - orb171649 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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