PDCD1LG2

Gene Symbol	PDCD1LG2
Entrez Gene	80380
Alt Symbol	B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2
Species	Human
Gene Type	protein-coding
Description	programmed cell death 1 ligand 2
Other Description	B7 dendritic cell molecule|B7-DC|PD-1 ligand 2|PD-1-ligand 2|PDCD1 ligand 2|butyrophilin B7-DC|programmed death ligand 2
Swissprots	Q5T7Z6 Q6JXL8 Q9BQ51 Q6JXL9 Q14CN8
Accessions	EAW58762 Q9BQ51 AF329193 AAK31105 AF344424 AAK15370 AK001872 AY254343 AAP13471 AY271901 AAP49000 AY271902 AAP49001 BC074766 AAH74766 BC113678 AAI13679 BC113680 AAI13681 BC143920 BC143921 BX951459 CA442083 DQ336699 ABC59616 EF444806 ABO33153 HQ258142 ADR82896 XM_005251600 XP_005251657 NM_025239 NP_079515
Function	Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). {ECO:0000250}.
Subcellular Location	Isoform 1: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. {ECO:0000269|PubMed:11224527}.
Top Pathways	Cell adhesion molecules (CAMs)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human B7 DC protein fragment - ab191645 from Abcam Category Protein Prices $515.00 Sizes 200 µg Source HEK 293 cells Species Human

Active human B7 DC protein fragment - ab191980 from Abcam Category Protein Prices $536.00 Sizes 100 µg Source HEK 293 cells Species Human

Human B7 DC protein fragment - ab164273 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human B7 DC protein fragment - ab180337 from Abcam Category Protein Prices $357.00 Sizes 100 µg Source E. coli Species Human

Human B7 DC protein fragment - ab198636 from Abcam Category Protein Prices $625.00 Sizes 100 µg Source HEK 293 cells Species Human

PDCD1LG2 / CD273 / PD-L2 Blocking Peptide - LS-E1570 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDCD1LG2 / CD273 / PD-L2 Antibody Blocking Peptide - LS-E30320 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PD-L2/B7-DC/PDCD1LG2 Partial Recombinant Protein - H00080380-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

PD-L2/B7-DC/PDCD1LG2 Blocking Peptide - NBP1-76770PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

PD-L2/B7-DC/PDCD1LG2 Recombinant Protein - H00080380-G01-10ug from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

PDCD1LG2-Antibody-N-term-Blocking-peptide - BP12309a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PD-L2 Peptide - GTX85449-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Recombinant Human PD-L2/B7-DC Fc Chimera, CF - 1224-PL-100 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human PDCD1LG2 protein - orb180380 from Biorbyt Category Protein Prices $408.00, $595.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human TBPL1 protein - orb81262 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Human PDL2 Fc His tag protein - orb83096 from Biorbyt Category Protein Prices $434.00, $612.00 Sizes 100 μg, 200 μg Source Human Species Human

Human PDCD1LG2 (Fc Tag) protein - orb179664 from Biorbyt Category Protein Prices $434.00, $612.00 Sizes 100 μg, 200 μg Source Human Cells Species Human

Human PDL2 His tag protein - orb83265 from Biorbyt Category Protein Prices $434.00, $595.00 Sizes 50 μg, 100 μg Source Human Species Human

Cynomolgus PD-L2 protein - orb139469 from Biorbyt Category Protein Prices $434.00, $612.00 Sizes 100 μg, 200 μg Source Human Cells

Mouse PDL2 His tag protein - orb84689 from Biorbyt Category Protein Prices $510.00, $748.00 Sizes 100 μg, 200 μg Source Mouse Species Human

Cynomolgus PD-L2 protein (His Tag) - orb139470 from Biorbyt Category Protein Prices $434.00, $612.00 Sizes 100 μg, 200 μg Source Human Cells

PDCD1LG2 protein (His tag) - 80R-3890 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

CD273 / PDL2 (20-200, His-tag) - AR51577PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CD273 / PDL2 (20-200, His-tag) - AR51577PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

CD273 / PDL2 - H00080380-H01 from Acris Antibodies Category Protein Prices $570.00 Sizes 2 µg Source Human HEK293T cells Species Human

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