SPO11

Gene Symbol SPO11
Entrez Gene 23626
Alt Symbol CT35, SPATA43, TOPVIA
Species Human
Gene Type protein-coding
Description SPO11 meiotic protein covalently bound to DSB
Other Description SPO11 meiotic protein covalently bound to DSB homolog|cancer/testis antigen 35|meiotic recombination protein SPO11|spermatogenesis associated 43
Swissprots Q9NQM7 Q8N4V0 Q9NQM8 Q5TCI1 Q9Y5K1
Accessions AAX44047 EAW75526 EAW75527 Q9Y5K1 AF149310 AAD44812 AF169385 AAD52562 BC033591 AAH33591 XM_005260379 XP_005260436 XM_005260380 XP_005260437 XM_005260381 XP_005260438 XM_005260382 XP_005260439 XM_011528756 XP_011527058 XM_011528757 XP_011527059 NM_012444 NP_036576 NM_198265 NP_937998
Function Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination (By similarity). Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2 (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Highly expressed in testis.

Spo11 (C-4) - sc-377161 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Spo11 (C-4): sc-377161. Western blot analysis of Spo11 expression in Hep G2 (A), HeLa (B) and PC-3 (C) nuclear extracts.

Spo11 (H-300) - sc-33146 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Spo11 (L-13) - sc-22474 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SPO11 antibody - ab181495 from Abcam

Prices $370.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-SPO11 antibody (ab181495) at 3 µg/ml + Human testis tissue lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-SPO11 antibody - ab168262 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SPO11 antibody (ab168262) at 1 µg/mlLane 1 : SPO11 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-SPO11 antibody - C-terminal - ab187552 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SPO11 antibody - C-terminal (ab187552) at 1/1000 dilution + Mouse thymus total cell extract

Anti-SPO11 antibody - N-terminal - ab187554 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-SPO11 antibody - N-terminal (ab187554) at 1/1000 dilution + Mouse thymus total cell extract.

Anti-SPO11 Antibody (aa299-326, AP) - LS-C241195 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPO11 Antibody (aa299-326, APC) - LS-C241196 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPO11 Antibody (aa299-326, Biotin) - LS-C241197 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPO11 Antibody (aa299-326, PE) - LS-C241199 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPO11 Antibody (aa299-326, FITC) - LS-C241198 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPO11 Antibody (aa298-326) - LS-C325339 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPO11 Antibody (aa299-326, Azide-free, HRP) - LS-C248239 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPO11 Antibody (aa110-159) - LS-C81959 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-SPO11 Antibody (aa299-326) - LS-C157078 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SPO11 Antibody western blot of K562 cell line lysates (35 ug/lane). The SPO11 antibody detected the SPO11 protein (arrow).

SPO11 Antibody - NBP1-58172 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SPO11 Antibody [NBP1-58172] - Sample Tissue: Human 293T Antibody Dilution: 1.0 ug/ml

SPO11 Antibody - NBP2-20475 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SPO11 Antibody [NBP2-20475] - Sample (30 ug of whole cell lysate) A: NT2D1 10% SDS PAGE gel, diluted at 1:1000.

SPO11 Antibody - H00023626-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SPO11 Antibody [H00023626-D01P] - Analysis of SPO11 expression in transfected 293T cell line by SPO11 polyclonal antibody.Lane 1: SPO11 transfected lysate(40.40 KDa).Lane 2: Non-transfected lysate.

SPO11 Antibody - H00023626-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: SPO11 Antibody [H00023626-A01] - SPO11 polyclonal antibody (A01), Lot # 061025JCS1 Western Blot analysis of SPO11 expression in SJCRH30 ( Cat # L027V1 ).

SPO11 Antibody - H00023626-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

SPO11 Polyclonal Antibody - bs-9302R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SPO11 antibody produced in mouse - SAB1407237 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SPO11: <B>Cat. No. SAB1407237</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~39.4 kDa using SPO11 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-SPO11 antibody produced in rabbit - SAB1401596 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-SPO11, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401596</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~40.40 kDa using SPO11 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-SPO11 antibody produced in rabbit - SAB2102289 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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