SPO11

Gene Symbol	SPO11
Entrez Gene	23626
Alt Symbol	CT35, SPATA43, TOPVIA
Species	Human
Gene Type	protein-coding
Description	SPO11 meiotic protein covalently bound to DSB
Other Description	SPO11 meiotic protein covalently bound to DSB homolog|cancer/testis antigen 35|meiotic recombination protein SPO11|spermatogenesis associated 43
Swissprots	Q9NQM7 Q8N4V0 Q9NQM8 Q5TCI1 Q9Y5K1
Accessions	AAX44047 EAW75526 EAW75527 Q9Y5K1 AF149310 AAD44812 AF169385 AAD52562 BC033591 AAH33591 XM_005260379 XP_005260436 XM_005260380 XP_005260437 XM_005260381 XP_005260438 XM_005260382 XP_005260439 XM_011528756 XP_011527058 XM_011528757 XP_011527059 NM_012444 NP_036576 NM_198265 NP_937998
Function	Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination (By similarity). Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2 (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}.
Tissue Specificity	Highly expressed in testis.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SPO11 full length protein - ab132246 from Abcam Category Protein Source Wheat germ Species Human

Human SPO11 protein fragment - ab161724 from Abcam Category Protein Source Wheat germ Species Human

SPO11 Antibody Blocking Peptide - LS-E5178 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPO11 Antibody Blocking Peptide - LS-E19799 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SPO11 Protein - H00023626-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SPO11 Protein - H00023626-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SPO11-Antibody-C-term-Blocking-Peptide - BP17609b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPO11 Blocking Peptide - 33R-4380 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SPO11 - H00023626-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SPO11 - H00023626-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SPO11 - H00023626-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SPO11 - H00023626-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SPO11 fusion protein - ag4340 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Meiotic recombination protein SPO11(SPO11) - CSB-YP897506HU CSB-EP897506HU CSB-BP897506HU CSB-MP897506HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SPO11, Peptide - MBS428119 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

SPO11 Peptide, Human - M34GP15073H from Creative Peptides Category Peptide Source Synthetic. Species Human

Meiotic recombination protein SPO11 (SPO11), Recombinant Protein - MBS1345530 from MyBioSource Category Protein Prices $1,170.00, $1,170.00, $1,395.00, $1,395.00, $1,870.00, $1,870.00, $2,335.00, $2,335.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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