BVES

Gene Symbol	BVES
Entrez Gene	11149
Alt Symbol	HBVES, POP1, POPDC1
Species	Human
Gene Type	protein-coding
Description	blood vessel epicardial substance
Other Description	popeye domain containing 1|popeye domain-containing protein 1|popeye protein 1
Swissprots	E1P5D8 Q9HBV0 Q8IWC6 Q5T550 A8K1R4 Q8NE79 Q5T551 Q9UNG6
Accessions	EAW48430 EAW48431 EAW48432 Q8NE79 AF204172 AAG23405 AK289979 BAF82668 BC034425 AAH34425 BC040502 AAH40502 HQ447848 ADQ32332 XM_011535398 XP_011533700 NM_001199563 NP_001186492 NM_007073 NP_009004 NM_147147 NP_671488
Function	Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3- mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading. {ECO:0000269|PubMed:16188940}.
Subcellular Location	Lateral cell membrane {ECO:0000269|PubMed:16188940}. Cell junction, tight junction {ECO:0000269|PubMed:16188940}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle (By similarity). Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Detected at cell-cell contact but never observed at the free surface of epithelial cells. {ECO:0000250}.
Tissue Specificity	Expressed in epithelial cells (at protein level). Expressed in fetal and adult heart and skeletal muscle. {ECO:0000269|PubMed:10441744, ECO:0000269|PubMed:10882522, ECO:0000269|PubMed:16188940}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BVES full length protein - ab161323 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human BVES protein fragment - ab161324 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BVES Antibody Blocking Peptide - LS-E2112 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BVES Antibody Blocking Peptide - LS-E17030 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human BVES Protein - H00011149-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human BVES Protein - H00011149-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

BVES-Antibody-C-term-Blocking-peptide - BP13010b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BVES (GST Tag) protein - orb171574 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

BVES Blocking Peptide - 33R-10170 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

BVES - H00011149-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

BVES - H00011149-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

BVES - H00011149-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

BVES - H00011149-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

BVES fusion protein - Ag14601 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

BVES fusion protein - Ag3593 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human BVES, His-tagged - BVES-10339H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human BVES, GST-tagged - BVES-235H from Creative Biomart Category Protein Source E. coli Species Human

Human BVES / POPDC1 Protein (GST Tag) - 12508-H09E-20 from Sino Biological Category Protein Source E. coli Species Human

Recombinant Human BVES / POPDC1 Protein (GST tag) - PKSH030823 from Elabscience Category Protein Source E. coli Species Human

BVES Recombinant Protein Antigen - NBP1-83286PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BVES Protein - NBP1-83285PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

BVES Peptide, Human - M34GP01600H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human BVES / POPDC1 Protein (GST Tag) - 12508-H09E from ABclonal Category Protein Prices $138.00, $348.00 Sizes 20 µg, 100 µg Source E. coli Species Human

Blood vessel epicardial substance (BVES), Recombinant Protein - MBS7010493 from MyBioSource Category Protein Prices $1,170.00, $2,155.00, $3,360.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

BVES / POPDC1, Recombinant Protein - MBS2545493 from MyBioSource Category Protein Prices $375.00, $905.00 Sizes 20 µg, 100 µg Source E Coli

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