BVES

Gene Symbol	BVES
Entrez Gene	11149
Alt Symbol	HBVES, POP1, POPDC1
Species	Human
Gene Type	protein-coding
Description	blood vessel epicardial substance
Other Description	popeye domain containing 1|popeye domain-containing protein 1|popeye protein 1
Swissprots	E1P5D8 Q9HBV0 Q8IWC6 Q5T550 A8K1R4 Q8NE79 Q5T551 Q9UNG6
Accessions	EAW48430 EAW48431 EAW48432 Q8NE79 AF204172 AAG23405 AK289979 BAF82668 BC034425 AAH34425 BC040502 AAH40502 HQ447848 ADQ32332 XM_011535398 XP_011533700 NM_001199563 NP_001186492 NM_007073 NP_009004 NM_147147 NP_671488
Function	Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3- mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading. {ECO:0000269|PubMed:16188940}.
Subcellular Location	Lateral cell membrane {ECO:0000269|PubMed:16188940}. Cell junction, tight junction {ECO:0000269|PubMed:16188940}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle (By similarity). Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Detected at cell-cell contact but never observed at the free surface of epithelial cells. {ECO:0000250}.
Tissue Specificity	Expressed in epithelial cells (at protein level). Expressed in fetal and adult heart and skeletal muscle. {ECO:0000269|PubMed:10441744, ECO:0000269|PubMed:10882522, ECO:0000269|PubMed:16188940}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BVES (E-3) - sc-374081 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

BVES (C-20) - sc-49889 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

BVES (H-4) - sc-374082 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

BVES (H-300) - sc-134807 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-BVES antibody - ab77639 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-BVES antibody - ab171550 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-BVES antibody - ab56814 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-BVES antibody - C-terminal - ab196551 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-BVES Antibody (aa313-342, AP) - LS-C252780 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BVES Antibody (aa313-342, APC) - LS-C252781 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BVES Antibody (clone 1C3) - LS-C139484 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1C3

Anti-BVES Antibody (aa313-342, FITC) - LS-C252783 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BVES Antibody (aa313-342, Biotin) - LS-C252782 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BVES Antibody (aa251-300) - LS-C111122 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-BVES Antibody - LS-C192233 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-BVES Antibody (aa313-342, PE) - LS-C252785 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BVES Antibody (aa313-342, Azide-free, HRP) - LS-C252784 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BVES Antibody (aa312-342) - LS-C319911 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BVES Antibody - LS-C330837 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-BVES Antibody (aa313-342) - LS-C156898 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

BVES Antibody - AF4986 from Novus Biologicals Prices $329.00 Sizes 100 µg Host Sheep Clonality Polyclonal

BVES Antibody (3F7) - H00011149-M02 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3F7

BVES Antibody - NBP1-83285 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BVES Antibody - NBP1-59647 from Novus Biologicals Prices $369.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

BVES Antibody - NBP1-83286 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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