DOK5

Gene Symbol DOK5
Entrez Gene 55816
Alt Symbol C20orf180, IRS-6, IRS6
Species Human
Gene Type protein-coding
Description docking protein 5
Other Description downstream of tyrosine kinase 5|insulin receptor substrate 6
Swissprots Q9BZ24 Q5TE53 Q8TEW7 Q9P104 Q5T7Y0 Q9Y411 Q96H13 Q9NQF4
Accessions EAW75570 EAW75571 Q9P104 AF132732 AAF66443 AF466368 AAL74194 AI822030 AK313222 AL050069 CAB43255 BC008992 AAH08992 BG212868 BI758267 BI916998 CN427887 DA161365 XM_011528903 XP_011527205 XM_011528904 XP_011527206 NM_001294161 NP_001281090 NM_018431 NP_060901 NM_177959 NP_808874
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Tissue Specificity Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes. {ECO:0000269|PubMed:12595900, ECO:0000269|PubMed:12730241}.

Dok-5 (C-15) - sc-27486 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dok-5 (C-15): sc-27486. Western blot analysis of Dok-5 expression in non-transfected: sc-110760 (A) and human Dok-5 transfected: sc-110916 (B) 293T whole cell lysates.

Dok-5 (E-16) - sc-27485 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dok-5 (E-16): sc-27485. Western blot analysis of Dok-5 expression in non-transfected: sc-110760 (A) and human Dok-5 transfected: sc-110916 (B) whole cell lysates.

Anti-DOK5 antibody - ab24360 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-DOK5 antibody (ab24360) at 0.1 µg/ml + Human kidney lysate (in RIPA buffer) at 35 µgdeveloped using the ECL techniqueObserved band size : 27 kDa (why is the actual band size different from the predicted?)Additional bands at : 21 kDa. We are unsure as to the identity of these extra bands.Exposure time : 1 hour

Anti-DOK5 antibody - ab80367 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DOK5 antibody (ab80367) at 1 µg/ml ( in 5% skim milk / PBS buffer) + placenta lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-DOK5 antibody [EPR9923(B)] - ab168343 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9923(B)
All lanes : Anti-DOK5 antibody [EPR9923(B)] (ab168343) at 1/10000 dilutionLane 1 : IM9 lysateLane 2 : Human fetal brain lysateLane 3 : Human fetal heart lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-DOK5 antibody - Aminoterminal end - ab71308 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-DOK5 antibody - Aminoterminal end (ab71308) at 1/100 dilution + Mouse liver tissue lysate at 12.5 µg

Anti-DOK5 antibody - Carboxyterminal end - ab71767 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-DOK5 antibody - Carboxyterminal end (ab71767) at 1/100 dilution + Mouse liver tissue lysate at 12.5 µg

Anti-DOK5 Antibody - LS-C317805 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Docking protein 5 antibody at 2 ug/ml with mouse kidney tissue Secondary Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 35 KDa. Observed band size: 35 KDa.

Anti-DOK5 Antibody (aa291-306) - LS-C147890 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (aa293-306) - LS-C54730 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.1 ug/ml) staining of human kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-DOK5 Antibody (aa20-49, AP) - LS-C234733 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (aa20-49, APC) - LS-C234735 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (aa20-49, Biotin) - LS-C234736 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (aa20-49, FITC) - LS-C234737 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (aa20-49, PE) - LS-C234741 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (C-Terminus, AP) - LS-C244215 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (C-Terminus, Biotin) - LS-C244218 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (C-Terminus, APC) - LS-C244216 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (C-Terminus, FITC) - LS-C244219 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (aa20-49, Azide-free, HRP) - LS-C249864 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (C-Terminus, PE) - LS-C244224 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (C-Terminus, Azide-free, HRP) - LS-C247547 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (aa38-87) - LS-C80512 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-DOK5 Antibody (FITC) - LS-C317801 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DOK5 Antibody (aa80-129) - LS-C291892 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Search more