DOK5

Gene Symbol DOK5
Entrez Gene 55816
Alt Symbol C20orf180, IRS-6, IRS6
Species Human
Gene Type protein-coding
Description docking protein 5
Other Description downstream of tyrosine kinase 5|insulin receptor substrate 6
Swissprots Q9BZ24 Q5TE53 Q8TEW7 Q9P104 Q5T7Y0 Q9Y411 Q96H13 Q9NQF4
Accessions EAW75570 EAW75571 Q9P104 AF132732 AAF66443 AF466368 AAL74194 AI822030 AK313222 AL050069 CAB43255 BC008992 AAH08992 BG212868 BI758267 BI916998 CN427887 DA161365 XM_011528903 XP_011527205 XM_011528904 XP_011527206 NM_001294161 NP_001281090 NM_018431 NP_060901 NM_177959 NP_808874
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Tissue Specificity Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes. {ECO:0000269|PubMed:12595900, ECO:0000269|PubMed:12730241}.

Dok-5 CRISPR/Cas9 KO Plasmid (h) - sc-412618 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-5 HDR Plasmid (h) - sc-412618-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-5 Double Nickase Plasmid (h) - sc-412618-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-5 Double Nickase Plasmid (h2) - sc-412618-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-5 CRISPR Activation Plasmid (h) - sc-412618-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-5 CRISPR Activation Plasmid (h2) - sc-412618-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-5 Lentiviral Activation Particles (h) - sc-412618-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-5 Lentiviral Activation Particles (h2) - sc-412618-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-5 siRNA (h) - sc-105314 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dok-5 shRNA Plasmid (h) - sc-105314-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dok-5 shRNA (h) Lentiviral Particles - sc-105314-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU089221 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7431 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7431 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06119 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06119

DOK5 siRNA (Human) - CRJ0946 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DOK5 - MBS8214079 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DOK5 (NM_018431.3) - SHH280317 from Creative biogene

Category siRNA
Species Reactivities Human

Human DOK5 siRNA - orb271447 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DOK5 shRNA Plasmid (Human) - CHJ0946 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DOK5 miRNA 3'UTR clone - MiUTR1H-02957 from Creative biogene

Species Reactivities Human
Search more