DOK5

Gene Symbol DOK5
Entrez Gene 55816
Alt Symbol C20orf180, IRS-6, IRS6
Species Human
Gene Type protein-coding
Description docking protein 5
Other Description downstream of tyrosine kinase 5|insulin receptor substrate 6
Swissprots Q9BZ24 Q5TE53 Q8TEW7 Q9P104 Q5T7Y0 Q9Y411 Q96H13 Q9NQF4
Accessions EAW75570 EAW75571 Q9P104 AF132732 AAF66443 AF466368 AAL74194 AI822030 AK313222 AL050069 CAB43255 BC008992 AAH08992 BG212868 BI758267 BI916998 CN427887 DA161365 XM_011528903 XP_011527205 XM_011528904 XP_011527206 NM_001294161 NP_001281090 NM_018431 NP_060901 NM_177959 NP_808874
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Tissue Specificity Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes. {ECO:0000269|PubMed:12595900, ECO:0000269|PubMed:12730241}.

Human-DOK5-cDNA-Clone - DC02555 from Abgent, a WuXi AppTec company

Prices $267.30
Sizes 10 µg
Species Human
Accession BC008992

DOK5 - MBS1267172 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC008992

Human DOK5 ORF Clone(NM_018431.3) - CDCR303751 from Creative biogene

Species Human

Human DOK5 ORF Clone (BC008992) - CDCS414792 from Creative biogene

Species Human
Accession Q9P104

Human DOK5 cDNA Clone(NM_018431.3) - CDFG001854 from Creative biogene

Species Human
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