DOK5

Gene Symbol	DOK5
Entrez Gene	55816
Alt Symbol	C20orf180, IRS-6, IRS6
Species	Human
Gene Type	protein-coding
Description	docking protein 5
Other Description	downstream of tyrosine kinase 5|insulin receptor substrate 6
Swissprots	Q9BZ24 Q5TE53 Q8TEW7 Q9P104 Q5T7Y0 Q9Y411 Q96H13 Q9NQF4
Accessions	EAW75570 EAW75571 Q9P104 AF132732 AAF66443 AF466368 AAL74194 AI822030 AK313222 AL050069 CAB43255 BC008992 AAH08992 BG212868 BI758267 BI916998 CN427887 DA161365 XM_011528903 XP_011527205 XM_011528904 XP_011527206 NM_001294161 NP_001281090 NM_018431 NP_060901 NM_177959 NP_808874
Function	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Tissue Specificity	Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes. {ECO:0000269|PubMed:12595900, ECO:0000269|PubMed:12730241}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DOK5 full length protein - ab163241 from Abcam Category Protein Source Wheat germ Species Human

Human DOK5 peptide - ab45623 from Abcam Category Peptide Species Human

Human DOK5 protein fragment - ab163242 from Abcam Category Protein Source Wheat germ Species Human

DOK5 Antibody Blocking Peptide - LS-E4784 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DOK5 Antibody Blocking Peptide - LS-E25776 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DOK5 Antibody Blocking Peptide - LS-E15657 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DOK5 Antibody Blocking Peptide - LS-E9197 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DOK5 Antibody Blocking Peptide - LS-E9198 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DOK5 Protein - H00055816-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human DOK5 Protein - H00055816-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

DOK5 Peptide - P2737 from Novus Biologicals Category Peptide Species Human

DOK5 Peptide - P2736 from Novus Biologicals Category Peptide Species Human

DOK5-Antibody-N-term-Blocking-Peptide - BP17160a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DOK5-Antibody-C-term-Blocking-Peptide - BP7693b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DOK5-Antibody-N-term-Blocking-Peptide - BP7693a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DOK5 blocking peptide - GTX89660-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Human DOK5 protein - orb244166 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

DOK5 Immunizing peptide - orb15708 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

DOK5 Blocking Peptide - 33R-3474 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DOK5 Peptide - AC21-0605-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

DOK5 - H00055816-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

DOK5 - H00055816-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DOK5 - H00055816-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DOK5 Peptide - 45-491P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

DOK5 fusion protein - ag2615 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

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