Gene Symbol | SGPP1 |
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Entrez Gene | 81537 |
Alt Symbol | SPPase1 |
Species | Human |
Gene Type | protein-coding |
Description | sphingosine-1-phosphate phosphatase 1 |
Other Description | hSPP1|hSPPase1|sphingosine-1-phosphatase 1|spp1 |
Swissprots | Q9H189 Q9BX95 B2RAH0 |
Accessions | EAW80834 Q9BX95 AF349315 AAK26660 AJ293294 CAC17772 AK314188 BAG36867 BC063839 AAH63839 BC070060 AAH70060 HY008514 XM_006720264 XP_006720327 NM_030791 NP_110418 |
Function | Has enzymatic activity against both sphingosine 1- phosphate (S1P) and dihydro-S1P. Regulates intracellular and extracellular S1P levels. {ECO:0000269|PubMed:12815058}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12815058}; Multi-pass membrane protein {ECO:0000269|PubMed:12815058}. |
Tissue Specificity | Ubiquitous, with the strongest level in placenta and kidney. {ECO:0000269|PubMed:12815058}. |
Top Pathways | Sphingolipid signaling pathway, Sphingolipid metabolism |
Human Spp1 gene - orb90939 from Biorbyt
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SGPP1 cDNA (ANA11427) - ANA11427 from Aviva Systems Biology
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SGPP1 cDNA (ANA11428) - ANA11428 from Aviva Systems Biology
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Human SGPP1 cDNA clone(NM_030791.2) - CDFG005166 from Creative Biomart
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Human SGPP1 cDNA clone(NM_030791.2) - CDFG005168 from Creative Biomart
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human SGPP1 ORF clone - CDCH079584 from Creative Biomart
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human SGPP1 ORF clone - CDCH079585 from Creative Biomart
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Human SGPP1 ORF Clone(NM_030791.2) - CDCL175325 from Creative Biomart
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Human SGPP1 ORF Clone(NM_030791.2) - CDCR310705 from Creative Biomart
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Human SGPP1 ORF Clone(NM_030791.2) - CDCR310706 from Creative Biomart
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Human SGPP1 ORF Clone(NM_030791.2) - CDCR310705 from Creative biogene
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Human SGPP1 cDNA Clone(NM_030791.2) - CDFG005166 from Creative biogene
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Human SGPP1 cDNA Clone(NM_030791.2) - CDFG005168 from Creative biogene
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Human Spp1 transcript variant 1 ORF Expression Clone, FLAG-tagged - orb145374 from Biorbyt
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