Gene Symbol | SGPP1 |
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Entrez Gene | 81537 |
Alt Symbol | SPPase1 |
Species | Human |
Gene Type | protein-coding |
Description | sphingosine-1-phosphate phosphatase 1 |
Other Description | hSPP1|hSPPase1|sphingosine-1-phosphatase 1|spp1 |
Swissprots | Q9H189 Q9BX95 B2RAH0 |
Accessions | EAW80834 Q9BX95 AF349315 AAK26660 AJ293294 CAC17772 AK314188 BAG36867 BC063839 AAH63839 BC070060 AAH70060 HY008514 XM_006720264 XP_006720327 NM_030791 NP_110418 |
Function | Has enzymatic activity against both sphingosine 1- phosphate (S1P) and dihydro-S1P. Regulates intracellular and extracellular S1P levels. {ECO:0000269|PubMed:12815058}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12815058}; Multi-pass membrane protein {ECO:0000269|PubMed:12815058}. |
Tissue Specificity | Ubiquitous, with the strongest level in placenta and kidney. {ECO:0000269|PubMed:12815058}. |
Top Pathways | Sphingolipid signaling pathway, Sphingolipid metabolism |
SGPP1 Antibody Blocking Peptide - LS-E2285 from LifeSpan Bioscience
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SGPP1 Antibody Blocking Peptide - LS-E18051 from LifeSpan Bioscience
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SPP1 / Osteopontin Antibody Blocking Peptide - LS-E1076 from LifeSpan Bioscience
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SPP1 / Osteopontin Antibody Blocking Peptide - LS-E8284 from LifeSpan Bioscience
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SPP1 / Osteopontin Antibody Blocking Peptide - LS-E13158 from LifeSpan Bioscience
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SPP1 / Osteopontin Antibody Blocking Peptide - LS-E31467 from LifeSpan Bioscience
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SPP1 / Osteopontin Antibody Blocking Peptide - LS-E25903 from LifeSpan Bioscience
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Human Osteopontin/OPN Biologically Active Protein - NBP2-36588 from Novus Biologicals
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Human Osteopontin/OPN Biologically Active Protein - NBP2-36502 from Novus Biologicals
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Recombinant Human Osteopontin/OPN Protein - NBP2-36518 from Novus Biologicals
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Osteopontin/OPN Recombinant Protein - H00006696-P01 from Novus Biologicals
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Osteopontin/OPN Partial Recombinant Protein - H00006696-Q01 from Novus Biologicals
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Osteopontin/OPN Partial Recombinant Protein - H00006696-Q02 from Novus Biologicals
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Recombinant Human Osteopontin/OPN Protein - NBC1-21056 from Novus Biologicals
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Osteopontin/OPN Blocking Peptide - NB600-1043PEP from Novus Biologicals
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SGPP1-Antibody-N-term-Blocking-Peptide - BP13228a from Abgent, a WuXi AppTec company
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Osteopontin Recombinant Protein (Active) - GTX48134-PRO from GeneTex
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Human Osteopontin His tag protein - orb83517 from Biorbyt
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Human Osteopontin protein - orb169345 from Biorbyt
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Human Osteopontin protein - orb80603 from Biorbyt
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SGPP1 Blocking Peptide - 33R-9107 from Fitzgerald
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SPP1 Blocking Peptide - 33R-6363 from Fitzgerald
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SPP1 Blocking Peptide - 33R-2174 from Fitzgerald
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SGPP1 control peptide - AP05169CP-N from Acris Antibodies
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SGPP1 fusion protein - Ag11914 from Proteintech Group
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