SGPP1

Gene Symbol	SGPP1
Entrez Gene	81537
Alt Symbol	SPPase1
Species	Human
Gene Type	protein-coding
Description	sphingosine-1-phosphate phosphatase 1
Other Description	hSPP1|hSPPase1|sphingosine-1-phosphatase 1|spp1
Swissprots	Q9H189 Q9BX95 B2RAH0
Accessions	EAW80834 Q9BX95 AF349315 AAK26660 AJ293294 CAC17772 AK314188 BAG36867 BC063839 AAH63839 BC070060 AAH70060 HY008514 XM_006720264 XP_006720327 NM_030791 NP_110418
Function	Has enzymatic activity against both sphingosine 1- phosphate (S1P) and dihydro-S1P. Regulates intracellular and extracellular S1P levels. {ECO:0000269|PubMed:12815058}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:12815058}; Multi-pass membrane protein {ECO:0000269|PubMed:12815058}.
Tissue Specificity	Ubiquitous, with the strongest level in placenta and kidney. {ECO:0000269|PubMed:12815058}.
Top Pathways	Sphingolipid signaling pathway, Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SPPase1 CRISPR/Cas9 KO Plasmid (h) - sc-405175 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SPPase1 HDR Plasmid (h) - sc-405175-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SPPase1 Double Nickase Plasmid (h) - sc-405175-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SPPase1 Double Nickase Plasmid (h2) - sc-405175-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SPPase1 CRISPR Activation Plasmid (h) - sc-405175-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SPPase1 CRISPR Activation Plasmid (h2) - sc-405175-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SPPase1 Lentiviral Activation Particles (h) - sc-405175-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SPPase1 Lentiviral Activation Particles (h2) - sc-405175-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SPPase1 siRNA (h) - sc-63060 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SPPase1 shRNA Plasmid (h) - sc-63060-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SPPase1 shRNA (h) Lentiviral Particles - sc-63060-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Osteopontin/OPN RNAi - H00006696-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Osteopontin/OPN RNAi - H00006696-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Osteopontin/OPN RNAi - H00006696-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU018071 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® Human Phosphatase - SIHP0853 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0854 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0855 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN19236 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19236 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

SGPP1 siRNA (Human) - CRJ2983 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SGPP1 - MBS8207897 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human SGPP1 (NM_030791.2) - SHH406364 from Creative biogene Category siRNA Species Reactivities Human

Human SGPP1 siRNA - orb273484 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SGPP1 shRNA Plasmid (Human) - CHJ2983 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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