PACSIN2

Gene Symbol	PACSIN2
Entrez Gene	11252
Alt Symbol	SDPII
Species	Human
Gene Type	protein-coding
Description	protein kinase C and casein kinase substrate in neurons 2
Other Description	cytoplasmic phosphoprotein PACSIN2|protein kinase C and casein kinase substrate in neurons protein 2|syndapin 2|syndapin II|syndapin-2|syndapin-II|syndapin2
Swissprots	Q9UNF0 Q9Y4V2 Q96HV9 O95921 Q9NPN1 Q9H0D3
Accessions	EAW73277 EAW73278 Q9UNF0 AF128536 AAD41781 AL136845 CAB66779 AL389984 CAB97538 AY007086 BC008037 AAH08037 BI964045 CR456536 CAG30422 CR533523 CAG38554 CU013136 CAK54567 CU013424 CAK54866 DQ892911 ABM83837 DQ896161 ABM87160 XM_005261319 XP_005261376 XM_011529846 XP_011528148 XM_011529847 XP_011528149 XM_011529848 XP_011528150 XM_011529849 XP_011528151 XM_011529850 XP_011528152 XM_011529851 XP_011528153 XM_011529852 XP_011528154 XM_011529853 XP_011528155 NM_001184970 NP_001171899 NM_001184971 NP_001171900 NM_007229 NP_009160
Function	Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis. {ECO:0000269|PubMed:21610094, ECO:0000269|PubMed:21693584, ECO:0000269|PubMed:23129763, ECO:0000269|PubMed:23236520, ECO:0000269|PubMed:23596323}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Recycling endosome membrane. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection {ECO:0000250}. Membrane, caveola. Note=Detected at the neck of flask-shaped caveolae. Localization to tubular recycling endosomes probably requires interaction with MICALL1 and EHD1.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:11082044, ECO:0000269|PubMed:11179684}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PACSIN2 Gene cDNA Clone - orb144592 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human-PACSIN2-cDNA-Clone - DC02314 from Abgent, a WuXi AppTec company Prices $656.10 Sizes 10 µg Species Human Accession BC008037

PACSIN2 - MBS1270692 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC008037

Human PACSIN2 cDNA clone(NM_001184970.1) - CDFH013596 from Creative Biomart Species Human Accession NM_001184970.1

Human PACSIN2 cDNA clone(NM_001184971.1) - CDFH013597 from Creative Biomart Species Human Accession NM_001184971.1

Human PACSIN2 ORF Clone(NM_001184970.1) - CDCR357701 from Creative Biomart Species Human Accession NM_001184970.1

Human PACSIN2 ORF Clone(NM_001184970.1) - CDCR357702 from Creative Biomart Species Human Accession NM_001184970.1

Human PACSIN2 ORF Clone(NM_001184971.1) - CDCR357704 from Creative Biomart Species Human Accession NM_001184971.1

Human PACSIN2 ORF Clone(NM_001184971.1) - CDCR357705 from Creative Biomart Species Human Accession NM_001184971.1

Human PACSIN2 Gene ORF cDNA clone in cloning vector - HG15007-G from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15007-ANG from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15007-ACG from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15007-NF from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15007-NY from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid, N-His tag - HG15007-NH from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15007-NM from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15007-CF from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15007-ACR from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15007-ANR from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15007-CM from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid - HG15007-UT from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid, C-His tag - HG15007-CH from Sino Biological Species Human

Human PACSIN2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG15007-CY from Sino Biological Species Human

Human PACSIN2 ORF Clone(NM_001184970.1) - CDCR357701 from Creative biogene Species Human

Mouse PACSIN2 ORF clone (NM_001184971.1) - CDCL145499 from Creative biogene Species Human

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