KAT6A

Gene Symbol KAT6A
Entrez Gene 7994
Alt Symbol MOZ, MRD32, MYST-3, MYST3, RUNXBP2, ZC2HC6A, ZNF220
Species Human
Gene Type protein-coding
Description K(lysine) acetyltransferase 6A
Other Description MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3|MYST histone acetyltransferase (monocytic leukemia) 3|histone acetyltransferase KAT6A|histone acetyltransferase MYST3|monocytic leukemia zinc finger protein|runt-related transcription factor binding protein 2|zinc finger protein 220
Swissprots Q92794
Accessions CCQ43374 EAW63239 EAW63240 Q92794 AA310750 AJ420560 AK128323 BC018011 BC142659 AAI42660 BC142959 AAI42960 BC172379 AAI72379 BP248857 BP271264 BP348860 CB216817 DA257528 DA442995 DA758316 U47742 AAC50662 XM_011544656 XP_011542958 XM_011544657 XP_011542959 XM_011544658 XP_011542960 XM_011544659 XP_011542961 XM_011544660 XP_011542962 NM_001305878 NP_001292807 NM_006766 NP_006757 NM_001099412 NP_001092882 NM_001099413 NP_001092883
Function Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. {ECO:0000269|PubMed:11742995, ECO:0000269|PubMed:11965546, ECO:0000269|PubMed:12771199, ECO:0000269|PubMed:16387653, ECO:0000269|PubMed:17925393, ECO:0000269|PubMed:23431171}.
Subcellular Location Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus, PML body. Note=Recruited into PML body after DNA damage.
Top Pathways Signaling pathways regulating pluripotency of stem cells

Panoply™ Human KAT6A Knockdown Stable Cell Line - CSC-DC007896 from Creative biogene

Category Cell Line
Species Human
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