Gene Symbol | KAT6A |
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Entrez Gene | 7994 |
Alt Symbol | MOZ, MRD32, MYST-3, MYST3, RUNXBP2, ZC2HC6A, ZNF220 |
Species | Human |
Gene Type | protein-coding |
Description | K(lysine) acetyltransferase 6A |
Other Description | MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3|MYST histone acetyltransferase (monocytic leukemia) 3|histone acetyltransferase KAT6A|histone acetyltransferase MYST3|monocytic leukemia zinc finger protein|runt-related transcription factor binding protein 2|zinc finger protein 220 |
Swissprots | Q92794 |
Accessions | CCQ43374 EAW63239 EAW63240 Q92794 AA310750 AJ420560 AK128323 BC018011 BC142659 AAI42660 BC142959 AAI42960 BC172379 AAI72379 BP248857 BP271264 BP348860 CB216817 DA257528 DA442995 DA758316 U47742 AAC50662 XM_011544656 XP_011542958 XM_011544657 XP_011542959 XM_011544658 XP_011542960 XM_011544659 XP_011542961 XM_011544660 XP_011542962 NM_001305878 NP_001292807 NM_006766 NP_006757 NM_001099412 NP_001092882 NM_001099413 NP_001092883 |
Function | Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. {ECO:0000269|PubMed:11742995, ECO:0000269|PubMed:11965546, ECO:0000269|PubMed:12771199, ECO:0000269|PubMed:16387653, ECO:0000269|PubMed:17925393, ECO:0000269|PubMed:23431171}. |
Subcellular Location | Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus, PML body. Note=Recruited into PML body after DNA damage. |
Top Pathways | Signaling pathways regulating pluripotency of stem cells |
Human Histone acetyltransferase MYST3 peptide - ab41910 from Abcam
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Human Histone acetyltransferase MYST3 protein fragment - ab159926 from Abcam
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MYST3 / MOZ Antibody Blocking Peptide - LS-E1489 from LifeSpan Bioscience
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MYST3 / MOZ Antibody Blocking Peptide - LS-E27085 from LifeSpan Bioscience
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Recombinant Human MYST3 Protein - H00007994-Q01 from Novus Biologicals
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MOZMYST3-Antibody-C-term-Blocking-peptide - BP12197b from Abgent, a WuXi AppTec company
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KAT6A blocking peptide - GTX88406-PEP from GeneTex
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Histone Acetyltransferase MYST3 Peptide - AC21-1907-P from Abcore
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MYST3 - H00007994-Q01-10 from Acris Antibodies
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MYST3 - H00007994-Q01-25 from Acris Antibodies
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MYST3 Control Peptide - AP00341CP-N from Acris Antibodies
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MOZ Peptide - 42-161P from ProSci
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Recombinant Human Histone acetyltransferase KAT6A(KAT6A) ,partial - CSB-YP856424HU CSB-EP856424HU CSB-BP856424HU CSB-MP856424HU from Cusabio
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Kat6a antibody ( mAb ) , 100 ug - HM-AB1663 from Novatein Biosciences
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Kat6a antibody ( mAb ) , 10 ug - HM-AB1664 from Novatein Biosciences
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MOZMYST3-Antibody-N-term-Blocking-Peptide - BP1115a from Abgent, a WuXi AppTec company
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KAT6A Peptide, Human - M34GP07896H from Creative Peptides
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MYST3 Recombinant Protein Antigen - NBP2-56972PEP from Novus Biologicals
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MYST3 Recombinant Protein Antigen - NBP2-57745PEP from Novus Biologicals
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Histone acetyltransferase KAT6A (KAT6A), partial, Recombinant Protein - MBS1429032 from MyBioSource
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MYST3 Immunizing peptide - orb59578 from Biorbyt
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Recombinant Human KAT6A Protein, GST-tagged - KAT6A-5866H from Creative Biomart
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