FGD5

Gene Symbol FGD5
Entrez Gene 152273
Alt Symbol ZFYVE23
Species Human
Gene Type protein-coding
Description FYVE, RhoGEF and PH domain containing 5
Other Description FYVE, RhoGEF and PH domain-containing protein 5|zinc finger FYVE domain-containing protein 23
Swissprots Q8IYP3 Q6ZNL6 B3KVQ3 Q6MZY1 Q8N8G4 Q8N861 Q7Z303
Accessions CCO13730 EAW64208 EAW64209 Q6ZNL6 AK057128 AK096856 BAC04878 AK097276 BAC04989 AK123054 BAG53865 AK131078 BAC85128 BC035364 AAH35364 BC040614 BC132814 AAI32815 BC132816 AAI32817 BC144300 AAI44301 BX538312 CAD98090 BX640820 CAE45896 JF432210 ADZ15427 XM_011533422 XP_011531724 XM_011533423 XP_011531725 XM_011533424 XP_011531726 NM_152536 NP_689749
Function Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape. {ECO:0000269|PubMed:22328776}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000269|PubMed:22328776}. Cell projection, ruffle membrane {ECO:0000269|PubMed:22328776}. Endoplasmic reticulum {ECO:0000269|PubMed:22328776}. Golgi apparatus {ECO:0000269|PubMed:22328776}. Early endosome {ECO:0000269|PubMed:22328776}. Note=In peripheral membrane ruffles, colocolizes with F-actin. In confluent HUVECs, detected at cell-cell-contact sites where it colocalizes with vascular endothelial cadherin/CDH5.
Tissue Specificity Expressed in endothelial cells (at protein level). {ECO:0000269|PubMed:22328776}.

FGD5 (C-15) - sc-102518 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FGD5 (C-15): sc-102518. Western blot analysis of FGD5 expression in 293T whole cell lysate.

Anti-FGD5 antibody - ab157485 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-FGD5 antibody (ab157485) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : HepG2 cell lysate

Anti-FGD5 antibody - ab67681 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-FGD5 antibody (ab67681) at 1/500 dilutionLane 1 : FGD5 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilutionObserved band size : 65 kDa (why is the actual band size different from the predicted?)

Anti-FGD5 Antibody - LS-C307524 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-FGD5 Antibody - LS-C332644 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using FGD5 antibody.

Anti-FGD5 Antibody (aa463-512) - LS-C187020 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human U937. FGD5 antibody dilution 1.0 ug/ml.

Anti-FGD5 Antibody (aa391-540) - LS-C179165 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FGD5 Antibody - NBP1-83878 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: FGD5 Antibody [NBP1-83878] - Staining of human cell line A-431 shows positivity in nuclei but not nucleoli.

FGD5 Antibody - NBP1-83877 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: FGD5 Antibody [NBP1-83877] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli and cytoplasm.

FGD5 Antibody - H00152273-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: FGD5 Antibody [H00152273-B01P] - Analysis of FGD5 expression in transfected 293T cell line by FGD5 polyclonal antibody. Lane 1: FGD5 transfected lysate(59.4 KDa). Lane 2: Non-transfected lysate.

Anti-FGD5 antibody produced in rabbit - HPA019191 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FGD5: <B>Cat. No. HPA019191</B>: Immunohistochemical staining of human urinary bladder shows strong cytoplasmic positivity in urothelial cells.

Anti-FGD5 antibody produced in rabbit - HPA014536 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FGD5: <B>Cat. No. HPA014536</B>: Immunohistochemical staining of human placenta shows strong positivity in Syncytiotrophoblasts.

Anti-FGD5 antibody produced in mouse - SAB1408389 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-FGD5: <B>Cat. No. SAB1408389</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~59.4 kDa using FGD5 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

FGD5 Antibody - C-terminal region (ARP70420_P050) - ARP70420_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FGD5 Polyclonal Antibody - A3553 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using FGD5 antibody.

FGD5 antibody - orb78456 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin embedded uriinary bladder carcinoma showing cytoplasmic staining using FGD5 antibody

FGD5 antibody - orb183686 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

FGD5 antibody - 70R-17288 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

FGD5 Antibody - abx036800 from Abbexa

Host Rabbit
Clonality Polyclonal

FGD5 Antibody - abx002565 from Abbexa

Host Rabbit
Clonality Polyclonal

FGD5 antibody - 20910-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded human lung using 20910-1-AP(FGD5 antibody) at dilution of 1:100 (under 10x lens)

FGD5 antibody - H00152273-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of FGD5 expression in transfected 293T cell line (H00152273-T01) by FGD5 MaxPab polyclonal antibody. Lane 1: FGD5 transfected lysate(59.4 KDa). Lane 2: Non-transfected lysate.

Anti-FGD5, Polyclonal Antibody - 25-A3553 from ARP American Research Products

Prices $299.00, $449.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal
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