MASP1

Gene Symbol	MASP1
Entrez Gene	5648
Alt Symbol	3MC1, CRARF, CRARF1, MAP1, MASP, MASP3, MAp44, PRSS5, RaRF
Species	Human
Gene Type	protein-coding
Description	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
Other Description	Ra-reactive factor serine protease p100|complement factor MASP-3|complement-activating component of Ra-reactive factor|mannan-binding lectin serine protease 1|mannose-binding lectin-associated serine protease 1|mannose-binding protein-associated serine protease|serine protease 5
Swissprots	Q9UF09 Q96RS4 Q68D21 Q8IUV8 P48740 O95570 A8K542 B4E2L7 A8K6M1
Accessions	BAA34864 BAA89206 EAW78150 EAW78151 EAW78152 EAW78153 P48740 AF284421 AAK84071 AI278088 AI828640 AK129893 AK291157 BAF83846 AK291686 BAF84375 AK300663 BAG62349 AK304334 BAG65179 AL134380 AL137646 CAB70856 AL708781 AV686235 BC039724 AAH39724 BC106945 AAI06946 BC106946 AAI06947 BX641029 CAE46018 BX647237 CAI46037 CB162101 CR749615 CAH18409 DC423174 XM_006713700 XP_006713763 XM_006713701 XP_006713764 XM_011512989 XP_011511291 XM_011512990 XP_011511292 XM_011512991 XP_011511293 NM_001031849 NP_001027019 NM_001879 NP_001870 NM_139125 NP_624302 NR_033519
Function	Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. {ECO:0000269|PubMed:11485744}.
Subcellular Location	Secreted {ECO:0000269|PubMed:11485744}.
Tissue Specificity	Protein of the plasma which is primarily expressed by liver. {ECO:0000269|PubMed:11485744, ECO:0000269|PubMed:8018603, ECO:0000269|PubMed:8240317, ECO:0000269|PubMed:9367419}.
Top Pathways	Complement and coagulation cascades, Staphylococcus aureus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MASP1 / MASP ELISA Kit (Sandwich ELISA) - LS-F5691 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 44.48 pg/ml Range 93.75-6000 pg/ml

Mouse MASP1 / MASP ELISA Kit (Sandwich ELISA) - LS-F5806 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 15.6 pg/ml Range 93.75-6000 pg/ml

Human MASP1 / MASP ELISA Kit (Sandwich ELISA) - LS-F12004 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 1.56 Range 93.75-6000 pg/ml

Human MASP ELISA Kit - abx054846 from Abbexa Category ELISA Kit

Human MASP1 ELISA Kit - abx152275 from Abbexa Category ELISA Kit Sensitivity 38.62 pg/ml Range 93.75 pg/ml - 6000 pg/ml

Mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) (MASP1), Human, ELISA Kit - CSB-E17965h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Mannan-binding lectin serine protease 1, MASP1, Human, ELISA Kit - E1895h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 1.56-100 U/L

Mannose Associated Serine Protease 1 (MASP1), Human, ELISA Kit - SEB895Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 32.12pg/mL Range 93.75-6,000pg/mL

Mannan Binding Lectin Associated Serine Protease, MASP, Human, ELISA Kit - E-EL-H1303 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Mannan Associated Serine Protease 1, MASP1, Human, ELISA Kit - E-EL-H2387 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 56.25 Range 93.75-6000pg/mL

Mannan Binding Lectin Associated Serine Protease, MASP, Rabbit, ELISA Kit - E-EL-RB2229 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Mannan Associated Serine Protease 1, MASP1, Rabbit, ELISA Kit - E-EL-RB1012 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Mannan Binding Lectin Associated Serine Protease, MASP, Chicken, ELISA Kit - E-EL-Ch0189 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Mannan Associated Serine Protease 1, MASP1, Chicken, ELISA Kit - E-EL-Ch1247 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Mannan Binding Lectin Associated Serine Protease, MASP, Porcine, ELISA Kit - E-EL-P1324 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Mannan Associated Serine Protease 1, MASP1, Porcine, ELISA Kit - E-EL-P1955 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Mannan Binding Lectin Associated Serine Protease, MASP, Sheep, ELISA Kit - E-EL-S0990 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Mannan Binding Lectin Associated Serine Protease, MASP, Monkey, ELISA Kit - E-EL-MK1119 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Mannan Associated Serine Protease 1, MASP1, Monkey, ELISA Kit - E-EL-MK2053 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Human MASP ELISA Kit - HM0237 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine MASP ELISA Kit - AM0237 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

MASP, ELISA Kit - MBS2507547 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

MASP, ELISA Kit - MBS2504554 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.375ng/mL Range 0.625-40ng/mL

MASP, ELISA Kit - MBS2500515 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

MASP, ELISA Kit - MBS2513881 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/mL Range 0.781-50ng/mL

Search more