POT1

Gene Symbol	POT1
Entrez Gene	25913
Alt Symbol	CMM10, HPOT1
Species	Human
Gene Type	protein-coding
Description	protection of telomeres 1
Other Description	POT1-like telomere end-binding protein|protection of telomeres 1 homolog|protection of telomeres protein 1
Swissprots	O95018 Q9NW19 Q9H662 Q9UG95 Q5MJ36 Q9NUX5
Accessions	AAD08852 CAE89907 CAE91483 EAW83615 EAW83616 EAW83617 Q9NUX5 AK001230 BAA91568 AK001935 BAA91988 AK022580 BAB14110 AK026234 BAB15404 AK302263 BAH13661 AL050120 CAB43281 AY823520 AAW22613 AY823521 AAW22614 AY823522 AAW22615 AY823523 AAW22616 AY823524 AAW22617 BC002923 AAH02923 BM693856 DA412639 DA580630 DA707481 DQ892765 ABM83691 DQ896010 ABM87009 XM_006715917 XP_006715980 XM_011516006 XP_011514308 XM_011516007 XP_011514309 NM_001042594 NP_001036059 NM_015450 NP_056265 NR_003102 NR_003103 NR_003104
Function	Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. Is a component of the double-stranded telomeric DNA- binding TRF1 complex which is involved in the regulation of telomere length by cis-inhibition of telomerase. Also acts as a single-stranded telomeric DNA-binding protein and thus may act as a downstream effector of the TRF1 complex and may transduce information about telomere maintenance and/or length to the telomere terminus. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Binds to two or more telomeric single-stranded 5'-TTAGGG-3' repeats (G-strand) and with high
Subcellular Location	Nucleus {ECO:0000269|PubMed:12391173}. Chromosome, telomere {ECO:0000269|PubMed:12391173}. Note=Colocalizes with telomeric DNA.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:11349150, ECO:0000269|PubMed:12391173}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human POT1 ELISA Kit (Sandwich ELISA) - LS-F8791 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.118 ng/ml Range 0.313-20 ng/ml

Human POT1 ELISA Kit - abx152802 from Abbexa Category ELISA Kit Sensitivity 0.114 ng/ml Range 0.313 ng/ml - 20 ng/ml

Protection Of Telomeres 1 Homolog (POT1), Human, ELISA Kit - SEK108Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.114ng/mL Range 0.312-20ng/mL

Protection of telomeres protein 1 (POT1), Human, ELISA Kit - CSB-EL018382HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

POT1, ELISA Kit - MBS2515741 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

Protectin (CD59), ELISA Kit - MBS2022041 from MyBioSource Category ELISA Kit Prices $355.00, $540.00, $730.00, $2,985.00, $5,410.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 25.7pg/mL. Range 62.5-4,000pg/mL. The standard curve concentrations used for the ELISA's were 4,000pg/mL, 2,000pg/mL, 1,000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL.

Protection of Telomeres 1 Homolog, ELISA Kit - MBS063237 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS068874 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS093962 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog - MBS054815 from MyBioSource Category ELISA Kit Prices $435.00, $600.00 Sizes 48 strip wells, 96 strip wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS065060 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS055108 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS062807 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS047708 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS054649 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS071041 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS053892 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS078735 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS100751 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS056463 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS053139 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS100252 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS080327 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS103114 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protection of Telomeres 1 Homolog, ELISA Kit - MBS067278 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more