Gene Symbol | PAPPA2 |
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Entrez Gene | 60676 |
Alt Symbol | PAPP-A2, PAPP-E, PAPPE, PLAC3 |
Species | Human |
Gene Type | protein-coding |
Description | pappalysin 2 |
Other Description | pappalysin-2|placenta-specific 3|pregnancy-associated plasma preproprotein-A2|pregnancy-associated plasma protein E1 |
Swissprots | A9Z1Y8 Q9BXP8 Q96PH7 Q96PH8 Q9H4C9 |
Accessions | CAD35982 CCD35052 EAW91003 EAW91004 Q9BXP8 AB209369 BAD92606 AF311940 AAK31073 AF342989 AAL17779 AF342990 AAL17780 AJ278348 CAC11134 AK096718 BC062665 BC104644 BC117193 AAI17194 BC117195 AAI17196 BC152552 BC156074 AAI56075 BC157039 AAI57040 BX649062 XM_005245422 XP_005245479 XM_011509857 XP_011508159 XM_011509858 XP_011508160 XM_011509859 XP_011508161 XR_921907 NM_020318 NP_064714 NM_021936 NP_068755 |
Function | Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3. {ECO:0000269|PubMed:11264294}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Expressed abundantly in placenta, and non- pregnant mammary gland with low expression in the kidney, fetal brain and pancreas. {ECO:0000269|PubMed:11264294, ECO:0000269|PubMed:11597188}. |
PAPPA2 / Pappalysin 2 Antibody Blocking Peptide - LS-E31017 from LifeSpan Bioscience
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PAPPA2 / Pappalysin 2 Antibody Blocking Peptide - LS-E15671 from LifeSpan Bioscience
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PAPPA2 / Pappalysin 2 Antibody Blocking Peptide - LS-E15670 from LifeSpan Bioscience
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Pappalysin-2/PAPP-A2 Blocking Peptide - NBP1-76487PEP from Novus Biologicals
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PLAC3 Peptide - GTX85150-PEP from GeneTex
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Recombinant Human Pappalysin-2/PAPP-A2, CF - 1668-ZN-020 from R&D Systems
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Human PAPPA2 protein (His Tag) - orb139449 from Biorbyt
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PAPPA2 Blocking Peptide - 33R-7246 from Fitzgerald
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PAPPA2 Blocking Peptide - 33R-1360 from Fitzgerald
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Human Pappalysin 2 Protein - abx068417 from Abbexa
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Human Pappalysin 2 Protein - abx068418 from Abbexa
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Pappalysin-2 / PAPPA2 control peptide - AP26287CP-N from Acris Antibodies
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Pappalysin 2 (PAPPA2), Human - 20-8803 from ARP American Research Products
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Pappalysin 2 (PAPPA2), Human - 20-8804 from ARP American Research Products
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PLAC3 Peptide - 6019P from ProSci
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Recombinant Human PAPPA2, His tagged - PAPPA2-821H from Creative Biomart
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Recombinant Pappalysin 2 (PAPPA2) - RPD471Hu01 from Uscn Life Science Inc.
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Recombinant Pappalysin 2 (PAPPA2) - RPD471Hu02 from Uscn Life Science Inc.
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Human PAPPA2 / Pappalysin 2 Protein (His Tag) - 10528-H08H-20 from Sino Biological
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Recombinant Pappalysin 2 (PAPPA2) - RPD471Hu01 from Cloud-clone
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Recombinant Pappalysin 2 (PAPPA2) - RPD471Hu02 from Cloud-clone
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Recombinant Human Pappalysin-2(PAPPA2) ,partial - CSB-YP871602HU CSB-EP871602HU CSB-BP871602HU CSB-MP871602HU from Cusabio
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Recombinant Human Pappalysin-2/PAPP-A2 Protein, CF - 1668-ZN from R&D Systems
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Pappalysin 2 (PAPPA2) - RPU143172 from Biomatik
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Pappalysin 2 (PAPPA2) - RPU143173 from Biomatik
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