Gene Symbol | PAPPA2 |
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Entrez Gene | 60676 |
Alt Symbol | PAPP-A2, PAPP-E, PAPPE, PLAC3 |
Species | Human |
Gene Type | protein-coding |
Description | pappalysin 2 |
Other Description | pappalysin-2|placenta-specific 3|pregnancy-associated plasma preproprotein-A2|pregnancy-associated plasma protein E1 |
Swissprots | A9Z1Y8 Q9BXP8 Q96PH7 Q96PH8 Q9H4C9 |
Accessions | CAD35982 CCD35052 EAW91003 EAW91004 Q9BXP8 AB209369 BAD92606 AF311940 AAK31073 AF342989 AAL17779 AF342990 AAL17780 AJ278348 CAC11134 AK096718 BC062665 BC104644 BC117193 AAI17194 BC117195 AAI17196 BC152552 BC156074 AAI56075 BC157039 AAI57040 BX649062 XM_005245422 XP_005245479 XM_011509857 XP_011508159 XM_011509858 XP_011508160 XM_011509859 XP_011508161 XR_921907 NM_020318 NP_064714 NM_021936 NP_068755 |
Function | Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3. {ECO:0000269|PubMed:11264294}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Expressed abundantly in placenta, and non- pregnant mammary gland with low expression in the kidney, fetal brain and pancreas. {ECO:0000269|PubMed:11264294, ECO:0000269|PubMed:11597188}. |
Anti-PAPP A2 antibody - ab117743 from Abcam
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Anti-PAPP A2 antibody - ab59094 from Abcam
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Anti-PAPP A2 antibody - ab59097 from Abcam
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Anti-PAPP A2 antibody - ab59099 from Abcam
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Anti-PAPP A2 antibody - ab59100 from Abcam
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Anti-PAPP A2 antibody - ab59101 from Abcam
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Anti-PAPP A2 antibody [MM0507-8M12] - ab89899 from Abcam
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Anti-PAPPA2 / Pappalysin 2 Antibody (aa888-1093, Biotin) - LS-C299612 from LifeSpan Bioscience
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Anti-PAPPA2 / Pappalysin 2 Antibody (aa888-1093, FITC) - LS-C302453 from LifeSpan Bioscience
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Anti-PAPPA2 / Pappalysin 2 Antibody (aa888-1093) - LS-C295751 from LifeSpan Bioscience
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Anti-PAPPA2 / Pappalysin 2 Antibody (aa432-481) - LS-C110700 from LifeSpan Bioscience
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Anti-PAPPA2 / Pappalysin 2 Antibody (aa108-157) - LS-C110699 from LifeSpan Bioscience
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Anti-PAPPA2 / Pappalysin 2 Antibody (N-Terminus) IHC-plus⢠- LS-B5346 from LifeSpan Bioscience
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Pappalysin-2/PAPP-A2 Antibody - AF1668 from Novus Biologicals
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Pappalysin-2/PAPP-A2 Antibody - NBP1-76487 from Novus Biologicals
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Pappalysin-2/PAPP-A2 Antibody - NBP1-87339 from Novus Biologicals
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Pappalysin-2/PAPP-A2 Antibody - NBP1-87340 from Novus Biologicals
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Pappalysin-2/PAPP-A2 Antibody [Biotin] - BAF1668 from Novus Biologicals
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PAPP A2 Polyclonal Antibody - bs-9916R from Bioss
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Anti-PAPPA2 (ab2) antibody produced in rabbit - SAB2101715 from Sigma-Aldrich
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Anti-PAPPA2 (ab1) antibody produced in rabbit - SAB2101714 from Sigma-Aldrich
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Anti-PLAC3 antibody produced in rabbit - SAB3500573 from Sigma-Aldrich
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PAPPA2 antibody - N-terminal region (ARP42555_P050) - ARP42555_P050 from Aviva Systems Biology
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PAPPA2 antibody - middle region (ARP42556_P050) - ARP42556_P050 from Aviva Systems Biology
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Pappalysin-2 antibody [8M12] - GTX52960 from GeneTex
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