MTHFS

Gene Symbol	MTHFS
Entrez Gene	10588
Alt Symbol	HsT19268
Species	Human
Gene Type	protein-coding
Description	5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
Other Description	5-formyltetrahydrofolate cyclo-ligase|methenyl-THF synthetase
Swissprots	H3BQ75 P49914
Accessions	EAW99132 P49914 AK054972 AL109717 AL110101 BC012417 AAH12417 BC019921 AAH19921 BC037852 BM313547 BM450865 CB995322 CK905549 DB464304 HG507300 L38928 AAC41945 NM_001199758 NP_001186687 NM_006441 NP_006432 NR_037654
Function	Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10- methenyltetrahydrofolate. {ECO:0000269|PubMed:8522195}.
Subcellular Location	Cytoplasm.
Top Pathways	One carbon pool by folate

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MTHFS overexpression lysate - LY416629 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MTHFS 293 Cell Lysate - 407765 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MTHFS Overexpression Lysate (Native) - NBL1-13366 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MTHFS (h): 293T Lysate - sc-113997 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

MTHFS Over-expression Lysate Product - GWB-B5F7C6 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human MTHFS Knockdown Stable Cell Line - CSC-DC009882 from Creative biogene Category Cell Line Species Human

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