MTHFS

Gene Symbol MTHFS
Entrez Gene 10588
Alt Symbol HsT19268
Species Human
Gene Type protein-coding
Description 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
Other Description 5-formyltetrahydrofolate cyclo-ligase|methenyl-THF synthetase
Swissprots H3BQ75 P49914
Accessions EAW99132 P49914 AK054972 AL109717 AL110101 BC012417 AAH12417 BC019921 AAH19921 BC037852 BM313547 BM450865 CB995322 CK905549 DB464304 HG507300 L38928 AAC41945 NM_001199758 NP_001186687 NM_006441 NP_006432 NR_037654
Function Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10- methenyltetrahydrofolate. {ECO:0000269|PubMed:8522195}.
Subcellular Location Cytoplasm.
Top Pathways One carbon pool by folate

MTHFS CRISPR/Cas9 KO Plasmid (h) - sc-411486 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTHFS HDR Plasmid (h) - sc-411486-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTHFS Double Nickase Plasmid (h) - sc-411486-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTHFS Double Nickase Plasmid (h2) - sc-411486-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTHFS CRISPR Activation Plasmid (h) - sc-411486-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTHFS CRISPR Activation Plasmid (h2) - sc-411486-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTHFS Lentiviral Activation Particles (h) - sc-411486-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTHFS Lentiviral Activation Particles (h2) - sc-411486-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTHFS siRNA (h) - sc-62649 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MTHFS shRNA Plasmid (h) - sc-62649-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MTHFS shRNA (h) Lentiviral Particles - sc-62649-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU048701 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14708 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14708 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00856 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00856

MTHFS siRNA (Human) - CRH7206 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MTHFS RNAi - H00010588-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human MTHFS (NM_006441.3) - SHH346364 from Creative biogene

Category siRNA
Species Reactivities Human

MTHFS shRNA Plasmid (Human) - CHH7206 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MTHFS miRNA 3'UTR clone - MiUTR3H-06633 from Creative biogene

Species Reactivities Human
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