MTHFS

Gene Symbol MTHFS
Entrez Gene 10588
Alt Symbol HsT19268
Species Human
Gene Type protein-coding
Description 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
Other Description 5-formyltetrahydrofolate cyclo-ligase|methenyl-THF synthetase
Swissprots H3BQ75 P49914
Accessions EAW99132 P49914 AK054972 AL109717 AL110101 BC012417 AAH12417 BC019921 AAH19921 BC037852 BM313547 BM450865 CB995322 CK905549 DB464304 HG507300 L38928 AAC41945 NM_001199758 NP_001186687 NM_006441 NP_006432 NR_037654
Function Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10- methenyltetrahydrofolate. {ECO:0000269|PubMed:8522195}.
Subcellular Location Cytoplasm.
Top Pathways One carbon pool by folate

MTHFS (D-11) - sc-390786 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MTHFS (D-11): sc-390786. Western blot analysis of MTHFS expression in non-transfected: sc-117752 (A) and human MTHFS transfected: sc-113997 (B) whole cell lysates.

MTHFS (FL-203) - sc-367351 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

MTHFS (G-8) - sc-398056 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MTHFS (G-8): sc-398056. Western blot analysis of MTHFS expression in non-transfected 293T: sc-117752 (A), human MTHFS transfected 293T: sc-113997 (B), Jurkat (C), MDA-MB-231 (D) and MDA-MB-435S (E) whole cell lysates.

MTHFS (G-18) - sc-66469 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MTHFS (G-18): sc-66469. Western blot analysis of MTHFS expression in non-transfected: sc-117752 (A) and human MTHFS transfected: sc-113997 (B) 293T whole cell lysates.

MTHFS (YZ-M) - sc-100563 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
MTHFS (YZ-M): sc-100563. Western blot analysis of MTHFS expression in HeLa whole cell lysate.

Anti-MTHFS antibody - ab82153 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-MTHFS antibody (ab82153) at 0.5 µg/ml + human liver lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-MTHFS antibody - ab56719 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MTHFS antibody - ab86682 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MTHFS antibody (ab86682) at 1 µg/ml + Transfected 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-MTHFS antibody - C-terminal - ab138467 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-MTHFS antibody - C-terminal (ab138467) at 1/100 dilution + Mouse spleen tissue lysates at 35 µg

Anti-HsT19268 / MTHFS Antibody (aa148-160) IHC-plus™ - LS-B10296 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-HsT19268 / MTHFS antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10296 concentration 5 ug/ml.

Anti-HsT19268 / MTHFS Antibody (aa133-159, APC) - LS-C223358 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HsT19268 / MTHFS Antibody (aa133-159, Biotin) - LS-C223360 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HsT19268 / MTHFS Antibody (aa133-159, AP) - LS-C223359 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HsT19268 / MTHFS Antibody (aa133-159, FITC) - LS-C223361 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HsT19268 / MTHFS Antibody (aa133-159, PE) - LS-C223363 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HsT19268 / MTHFS Antibody (aa133-159, Azide-free, HRP) - LS-C223362 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HsT19268 / MTHFS Antibody (aa104-204, Azide-free) - LS-C327942 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-HsT19268 / MTHFS Antibody (aa132-160) - LS-C323151 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HsT19268 / MTHFS Antibody (aa107-156) - LS-C111381 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MTHFS antibody LS-C111381 Western blot of Transfected 293T cell lysate.

Anti-HsT19268 / MTHFS Antibody (aa107-156) - LS-C102415 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MTHFS antibody LS-C102415 Western blot of Transfected 293T cell lysate.

Anti-HsT19268 / MTHFS Antibody (aa133-159) - LS-C158325 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MTHFS Antibody western blot of mouse spleen tissue lysates (35 ug/lane). The MTHFS antibody detected the MTHFS protein (arrow).

MTHFS Antibody - NBP1-83161 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: MTHFS Antibody [NBP1-83161] - Staining of human cell line A-431 shows positivity in plasma membrane, cytoplasm and golgi apparatus.

MTHFS Antibody - NBP2-19431 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MTHFS Antibody [NBP2-19431] - Sample (30 ug of whole cell lysate) A: A549 B: Hep G2 12% SDS PAGE gel, diluted at 1:1000.

MTHFS Antibody - NBP1-56698 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MTHFS Antibody [NBP1-56698] - Transfected 293T cell lysate, concentration 0.2-1 ug/ml.

MTHFS Antibody - NBP1-20947 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: MTHFS Antibody [NBP1-20947] - (0.5ug/ml) Analysis of Human Liver lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
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