TPM4

Gene Symbol TPM4
Entrez Gene 7171
Alt Symbol HEL-S-108
Species Human
Gene Type protein-coding
Description tropomyosin 4
Other Description TM30p1|epididymis secretory protein Li 108|tropomyosin alpha-4 chain|tropomyosin-4
Swissprots P67936 Q15659 Q9UCS4 Q9UCS1 Q9H8Q3 Q9UCS3 Q5U0D9 Q9UCS2 P07226 Q9BU85
Accessions EAW84521 EAW84522 EAW84523 EAW84524 P67936 AF186109 AAG17014 AK023385 BAB14554 AK095546 AK096732 AK300136 BAG61923 AK301285 BAG62844 AK307538 AK315076 BAG37545 BC002827 AAH02827 BC037576 AAH37576 BC067225 AAH67225 BT019634 AAV38440 DA032511 DC365500 FJ224305 ACI45997 M12127 AAA36774 X05276 CAA28888 XM_005260042 XP_005260099 XM_006722865 XP_006722928 XM_011528231 XP_011526533 XM_011528232 XP_011526534 NM_001145160 NP_001138632 NM_003290 NP_003281
Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium. {ECO:0000269|PubMed:1836432}.
Subcellular Location Cytoplasm, cytoskeleton.
Tissue Specificity Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets of hypertensive patients without cardiac hypertrophy (at protein level). {ECO:0000269|PubMed:1836432}.
Top Pathways Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes

Tropomyosin alpha-4 chain (TPM4), Human, ELISA Kit - CSB-EL024108HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

tropomyosin 4, ELISA Kit - MBS944560 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human TPM4 is typically less than 5.8 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 23.5 pg/ml -1500 pg/ml.

Human Tropomyosin alpha-4 chain(TPM4) ELISA kit - CSB-EL024108HU from Cusabio

Category ELISA Kit
Sensitivity 5.8 pg/ml.
Range 23.5 pg/ml-1500 pg/ml

Human Tropomyosin alpha-4 chain (TPM4) ELISA Kit - EKC35896 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 5.8 pg/ml
Range 23.5 pg/ml-1500 pg/ml

Human Tropomyosin alpha-4 chain ELISA Kit - EKE53736 from Biomatik

Category ELISA Kit
Prices $685.40, $2,912.95, $5,483.20
Sizes 96 t, 5x96t, 10x96t
Range 0.156-10 ng/ml

TPM4 ELISA Kit (Human) (OKEH02068) - OKEH02068 from Aviva Systems Biology

Category ELISA Kit
Prices $420.00
Sizes 96 wells
Sensitivity < 0.11 ng/mL
Range 0.156 - 10 ng/mL

Human TPM4 ELISA Kit - E039582 from Biobool

Category ELISA Kit
Sensitivity The minimum detectable dose of human TPM4 is typically less than 5.8 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean

Human Tropomyosin alpha-4 chain ELISA Kit - EK2572 from Signalway Antibody

Category ELISA Kit
Prices $599.00
Sizes 1x96t
Range 0.156-10 ng/ml

Tropomyosin alpha-4 chain, ELISA Kit - MBS2887757 from MyBioSource

Category ELISA Kit
Prices $380.00, $500.00, $2,170.00, $3,840.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 0.156-10 ng/ml

Tropomyosin alpha-4 chain, ELISA Kit - MBS9426411 from MyBioSource

Category ELISA Kit
Prices $555.00
Sizes 96 tests
Range 0.156-10 ng/mL

Tropomyosin alpha-4 chain, ELISA Kit - MBS2887872 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin alpha-4 chain, ELISA Kit - MBS2887871 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tropomyosin alpha-4 chain, ELISA Kit - MBS2887873 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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