TPM4

Gene Symbol TPM4
Entrez Gene 7171
Alt Symbol HEL-S-108
Species Human
Gene Type protein-coding
Description tropomyosin 4
Other Description TM30p1|epididymis secretory protein Li 108|tropomyosin alpha-4 chain|tropomyosin-4
Swissprots P67936 Q15659 Q9UCS4 Q9UCS1 Q9H8Q3 Q9UCS3 Q5U0D9 Q9UCS2 P07226 Q9BU85
Accessions EAW84521 EAW84522 EAW84523 EAW84524 P67936 AF186109 AAG17014 AK023385 BAB14554 AK095546 AK096732 AK300136 BAG61923 AK301285 BAG62844 AK307538 AK315076 BAG37545 BC002827 AAH02827 BC037576 AAH37576 BC067225 AAH67225 BT019634 AAV38440 DA032511 DC365500 FJ224305 ACI45997 M12127 AAA36774 X05276 CAA28888 XM_005260042 XP_005260099 XM_006722865 XP_006722928 XM_011528231 XP_011526533 XM_011528232 XP_011526534 NM_001145160 NP_001138632 NM_003290 NP_003281
Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium. {ECO:0000269|PubMed:1836432}.
Subcellular Location Cytoplasm, cytoskeleton.
Tissue Specificity Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets of hypertensive patients without cardiac hypertrophy (at protein level). {ECO:0000269|PubMed:1836432}.
Top Pathways Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes

Anti-TPM4 antibody - ab58332 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
TPM4 antibody (ab58332) used in immunofluorescence at 10ug/ml on HeLa cells.

Anti-TPM4 antibody - ab93645 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab93645, at 1/100 dilution, showing cytoplasmic staining of TPM4 in formalin-fixed, paraffin-embedded skeletal muscle by Immunohistochemistry.

Anti-TPM4 antibody - ab199885 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-TPM4 antibody (ab199885) at 1/1000 dilutionLane 1 : Mouse thymus total cell extractLane 2 : HeLa total cell extractLane 3 : Jurkat total cell extract

Anti-TPM4 antibody - ab112567 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-TPM4 antibody (ab112567) at 1/100 dilution + U251 Cell Lysate at 35 µg

Anti-TPM4 antibody [EPR13316] - ab181085 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13316
All lanes : Anti-TPM4 antibody [EPR13316] (ab181085) at 1/5000 dilutionLane 1 : HeLa whole cell lysateLane 2 : A549 whole cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilutiondeveloped using the ECL technique

Anti-TPM4 antibody [EPR13317] - ab181156 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13317
Immunohistochemical analysis of paraffin-embedded Human spleen tissue labeling TPM4 with ab181156 at 1/500 dilution followed by prediluted HRP Polymer for Rabbit IgG. Counter stained with Hematoxylin.

Anti-TPM4 Antibody - LS-C152838 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TPM4 Antibody (aa33-62, AP) - LS-C272018 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TPM4 Antibody (aa33-62, APC) - LS-C272019 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TPM4 Antibody (N-Terminus) - LS-C137094 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TPM4 Antibody (aa33-62, Biotin) - LS-C272020 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TPM4 Antibody (aa33-62, FITC) - LS-C272021 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TPM4 Antibody (aa33-62, PE) - LS-C272023 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TPM4 Antibody (aa33-62, Azide-free, HRP) - LS-C272022 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TPM4 Antibody (aa33-62) - LS-C325890 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TPM4 Antibody (C-Terminus) - LS-C345747 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of TPM4 Antibody with human MCF7 Whole Cell lysate.

Anti-TPM4 Antibody (aa33-62) - LS-C160141 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TPM4 Antibody western blot of U251,A549,Jurkat cell line lysates (35 ug/lane). The TPM4 antibody detected the TPM4 protein (arrow).

Anti-TPM4 Antibody (aa266-276) - LS-C305883 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
TPM4 antibody (0.03 ug/ml) staining of Human Platelets lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-TPM4 Antibody (clone 4E4-1D2) - LS-C133492 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4E4-1D2
Immunoperoxidase of monoclonal antibody to TPM4 on formalin-fixed paraffin-embedded human transitional cell carcinoma tissue. [antibody concentration 2 ug/ml].

tropomyosin-4 Antibody (4E4-1D2) - H00007171-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4E4-1D2
Western Blot: tropomyosin-4 Antibody (4E4-1D2) [H00007171-M01] - TPM4 monoclonal antibody (M01), clone 4E4-1D2 Analysis of TPM4 expression in Hela.

tropomyosin-4 Antibody - NBP2-15146 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: tropomyosin-4 Antibody [NBP2-15146] - Sample (30 ug of whole cell lysate) A: NT2D1 B: Hela 12% SDS PAGE; antibody diluted at 1:1000.

Anti-TPM4 antibody produced in rabbit - SAB2700503 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TPM4: <B>Cat. No. SAB2700503</B>: Immunohistochemical analysis of paraffin-embedded 4T1 xenograft, using Tropomyosin 4 antibody at 1:100 dilution.

ANTI-TPM4 (N-TERM) antibody produced in rabbit - SAB1304880 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-TPM4 (N-term): <B>Cat. No. SAB1304880</B>: TPM4 Antibody (N-term) western blot analysis in cell line lysates (35 μg/lane).<BR/><B>Lanes:</B><BR/>1. U251<BR/>2. A549<BR/>3. Jurkat

TPM4 Antibody - C-terminal region (ARP74302_P050) - ARP74302_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TPM4-Antibody-N-term - AP12756a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
TPM4 Antibody (N-term) (Cat. #AP12756a) western blot analysis in U251,A549,Jurkat cell line lysates (35ug/lane).This demonstrates the TPM4 antibody detected the TPM4 protein (arrow).
Search more