TFEC

Gene Symbol TFEC
Entrez Gene 22797
Alt Symbol TCFEC, TFE-C, TFEC-L, TFECL, bHLHe34, hTFEC-L
Species Human
Gene Type protein-coding
Description transcription factor EC
Other Description class E basic helix-loop-helix protein 34
Swissprots B2R8X5 Q8N6J9 Q709A4 O14948 Q5H9U8
Accessions AAS02009 AAS07449 EAL24366 EAW83490 EAW83491 EAW83492 O14948 AJ608795 CAE77680 AK301479 BAH13493 AK313546 BAG36322 BC029891 AAH29891 BX538223 CR933605 CAI45926 D43945 BAA21908 XM_011515963 XP_011514265 XM_011515964 XP_011514266 XM_011515965 XP_011514267 XM_011515966 XP_011514268 XM_011515967 XP_011514269 XM_011515968 XP_011514270 XM_011515969 XP_011514271 XM_011515970 XP_011514272 XM_011515971 XP_011514273 XM_011515972 XP_011514274 XM_011515973 XP_011514275 XM_011515974 XP_011514276 NM_001018058 NP_001018068 NM_001244583 NP_001231512 NM_012252 NP_036384
Function Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form. {ECO:0000250, ECO:0000269|PubMed:11467950, ECO:0000269|PubMed:9256061}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981, ECO:0000269|PubMed:11467950}.
Tissue Specificity Expressed moderately in spleen, kidney, bone marrow, small intestine and leukocytes. Expressed weakly in testis, trachea and colon. {ECO:0000269|PubMed:11467950, ECO:0000269|PubMed:15118077}.

TFEC (L-15) - sc-11013 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TFEC (L-15): sc-11013. Western blot analysis of TFEC expression in non-transfected: sc-117752 (A) and human TFEC transfected: sc-114466 (B) 293T whole cell lysates.

TFEC (H-17) - sc-11012 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TFEC (D-16) - sc-11017 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TFEC (H-68) - sc-292881 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

TFEC (X-24) - sc-134079 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal

Anti-TFEC antibody - ab115569 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Human spleen (formalin-fixed, paraffin-embedded) stained with ab115569 at 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-TFEC antibody - ab96719 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-TFEC antibody (ab96719) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-TFEC antibody - ab2653 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TFEC antibody [EPR14871] - ab185226 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14871
All lanes : Anti-TFEC antibody [EPR14871] (ab185226) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : HepG2 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-TFEC Antibody (aa71-120) - LS-C30504 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Jurkat Cell Lysate

Anti-TFEC Antibody (aa179-205, Biotin) - LS-C271344 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFEC Antibody (aa179-205, FITC) - LS-C271345 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFEC Antibody (aa179-205, Azide-free, HRP) - LS-C271346 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFEC Antibody (aa179-205, PE) - LS-C271347 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFEC Antibody (aa179-205) - LS-C325689 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFEC Antibody (aa1-43) - LS-C185660 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A:293T. 10% SDS PAGE. TFEC antibody. TFEC antibody diluted at 1:1000.

Anti-TFEC Antibody (aa179-205) - LS-C156208 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TFEC Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The TFEC antibody detected the TFEC protein (arrow).

Anti-TFEC Antibody (aa217-228) IHC-plus™ - LS-B2458 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-TFEC antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2458 concentration 5 ug/ml.

Anti-TFEC Antibody (aa179-205, AP) - LS-C271340 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFEC Antibody (aa2-13) - LS-C55581 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (1 ug/ml) of Human Testis lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Anti-TFEC Antibody (aa179-205, APC) - LS-C271343 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

TFEC Antibody - NB100-1031 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: TFEC Antibody [NB100-1031] - (1ug/ml) of Human Testis lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

TFEC Antibody (4F11) - H00022797-M08 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F11
Western Blot: TFEC Antibody (4F11) [H00022797-M08] - Analysis of TFEC expression in transfected 293T cell line by TFEC monoclonal antibody (M08), clone 4F11. Lane 1: TFEC transfected lysatE (22.7 KDa). Lane 2: Non-transfected lysate.

Monoclonal Anti-TFEC, (N-terminal) antibody produced in mouse - SAB1402542 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F11
<B>Immunoblotting</B><BR/>Monoclonal Anti-TFEC, antibody produced in mouse, clone 4F11, purified immunoglobulin: <B>Cat. No. SAB1402542</B>: Antibody concentration: 1 μg/mL. Specific band of ~35.9 kDa using immunogen protein lysate.

Anti-TFEC antibody produced in goat - SAB2501032 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-TFEC: <B>Cat. No. SAB2501032</B>: staining (1 μg/mL) of Human Testis lysate (RIPA buffer, 30 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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