TFEC

Gene Symbol	TFEC
Entrez Gene	22797
Alt Symbol	TCFEC, TFE-C, TFEC-L, TFECL, bHLHe34, hTFEC-L
Species	Human
Gene Type	protein-coding
Description	transcription factor EC
Other Description	class E basic helix-loop-helix protein 34
Swissprots	B2R8X5 Q8N6J9 Q709A4 O14948 Q5H9U8
Accessions	AAS02009 AAS07449 EAL24366 EAW83490 EAW83491 EAW83492 O14948 AJ608795 CAE77680 AK301479 BAH13493 AK313546 BAG36322 BC029891 AAH29891 BX538223 CR933605 CAI45926 D43945 BAA21908 XM_011515963 XP_011514265 XM_011515964 XP_011514266 XM_011515965 XP_011514267 XM_011515966 XP_011514268 XM_011515967 XP_011514269 XM_011515968 XP_011514270 XM_011515969 XP_011514271 XM_011515970 XP_011514272 XM_011515971 XP_011514273 XM_011515972 XP_011514274 XM_011515973 XP_011514275 XM_011515974 XP_011514276 NM_001018058 NP_001018068 NM_001244583 NP_001231512 NM_012252 NP_036384
Function	Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form. {ECO:0000250, ECO:0000269|PubMed:11467950, ECO:0000269|PubMed:9256061}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981, ECO:0000269|PubMed:11467950}.
Tissue Specificity	Expressed moderately in spleen, kidney, bone marrow, small intestine and leukocytes. Expressed weakly in testis, trachea and colon. {ECO:0000269|PubMed:11467950, ECO:0000269|PubMed:15118077}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TFEC full length protein - ab131877 from Abcam Category Protein Source Wheat germ Species Human

Human TFEC peptide - ab22928 from Abcam Category Peptide Species Human

Human TFEC protein fragment - ab161427 from Abcam Category Protein Source Wheat germ Species Human

TFEC Antibody Blocking Peptide - LS-E6660 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TFEC Antibody Blocking Peptide - LS-E25351 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TFEC Antibody Blocking Peptide - LS-E11282 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TFEC Antibody Blocking Peptide - LS-E26403 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TFEC Protein - H00022797-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human TFEC Protein - H00022797-P01 from Novus Biologicals Category Protein Prices $305.00, $445.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TFEC-AntibodyCenter-Blocking-peptide - BP19475c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TFEC blocking peptide - GTX89915-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

TFEC Protein Lysate (APL10563) - APL10563 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

TFEC Protein Lysate (APL10564) - APL10564 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

TFEC Peptide - AC21-0179-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TFEC - H00022797-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

TFEC - H00022797-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TFEC - H00022797-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TFEC Peptide - 46-483P from ProSci Category Peptide Species Human

TFEC fusion protein - ag4061 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Transcription factor EC(TFEC) - CSB-YP023430HU CSB-EP023430HU CSB-BP023430HU CSB-MP023430HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TFEC (full length, N-term HIS tag, transcript variant 2) - TP760879 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

TFEC, Peptide - MBS425377 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

TFEC Protein Lysate - orb333464 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

TFEC Peptide, Human - M34GP15847H from Creative Peptides Category Peptide Source Synthetic. Species Human

TFEC Protein Lysate - orb333463 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

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