TFEC

Gene Symbol TFEC
Entrez Gene 22797
Alt Symbol TCFEC, TFE-C, TFEC-L, TFECL, bHLHe34, hTFEC-L
Species Human
Gene Type protein-coding
Description transcription factor EC
Other Description class E basic helix-loop-helix protein 34
Swissprots B2R8X5 Q8N6J9 Q709A4 O14948 Q5H9U8
Accessions AAS02009 AAS07449 EAL24366 EAW83490 EAW83491 EAW83492 O14948 AJ608795 CAE77680 AK301479 BAH13493 AK313546 BAG36322 BC029891 AAH29891 BX538223 CR933605 CAI45926 D43945 BAA21908 XM_011515963 XP_011514265 XM_011515964 XP_011514266 XM_011515965 XP_011514267 XM_011515966 XP_011514268 XM_011515967 XP_011514269 XM_011515968 XP_011514270 XM_011515969 XP_011514271 XM_011515970 XP_011514272 XM_011515971 XP_011514273 XM_011515972 XP_011514274 XM_011515973 XP_011514275 XM_011515974 XP_011514276 NM_001018058 NP_001018068 NM_001244583 NP_001231512 NM_012252 NP_036384
Function Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form. {ECO:0000250, ECO:0000269|PubMed:11467950, ECO:0000269|PubMed:9256061}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981, ECO:0000269|PubMed:11467950}.
Tissue Specificity Expressed moderately in spleen, kidney, bone marrow, small intestine and leukocytes. Expressed weakly in testis, trachea and colon. {ECO:0000269|PubMed:11467950, ECO:0000269|PubMed:15118077}.

Transcription factor EC (TFEC), Human, ELISA Kit - E01T0681 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Human TFEC ELISA Kit - E038810 from Biobool

Category ELISA Kit

anti-TFEC antibody - ARG63214 from Arigo Biolaboratories

Category ELISA Kit
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