UGT1A6

Gene Symbol	UGT1A6
Entrez Gene	54578
Alt Symbol	GNT1, HLUGP, HLUGP1, UDPGT, UDPGT 1-6, UGT1, UGT1A6S, UGT1F
Species	Human
Gene Type	protein-coding
Description	UDP glucuronosyltransferase 1 family, polypeptide A6
Other Description	UDP glycosyltransferase 1 family, polypeptide A6|UDP-glucuronosyltransferase 1 family polypeptide A6s|UDP-glucuronosyltransferase 1-6|UDP-glucuronosyltransferase 1-F|UDP-glucuronosyltransferase 1A6|UGT-1F|UGT1*6|UGT1-06|UGT1.6|phenol-metabolizing UDP-glucuronosyltransferase
Swissprots	P19224 A6NKK6 Q96TE7 B8K289
Accessions	AAA61247 AAB87411 AAC41717 AAG30420 EAW71055 P19224 AY435141 AAR95642 BC011409 BC019861 AAH19861 BE463503 BM688740 BM924331 DB014621 DQ364250 ABC96774 J04093 AAA61251 NM_001072 NP_001063 NM_205862 NP_995584
Function	UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 3 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity). {ECO:0000250}.
Subcellular Location	Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity	Expressed in skin. Isoforms 1 and 3 are expressed in kidney and liver. Isoform 1 but not isoform 2 is expressed in colon, esophagus and small intestine. {ECO:0000269|PubMed:1339448, ECO:0000269|PubMed:18004212}.
Top Pathways	Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

human UGT1A6 ORF clone - CDCH097986 from Creative Biomart Species Human Accession NM_001072

human UGT1A6 ORF clone - CDCH097987 from Creative Biomart Species Human Accession NM_001072

human UGT1A6 ORF clone - CDCH097988 from Creative Biomart Species Human Accession NM_001072

human UGT1A6 ORF clone - CDCH097989 from Creative Biomart Species Human Accession NM_001072

Human UGT1A6 Gene ORF cDNA clone in cloning vector - HG13312-G from Sino Biological Species Human

Human UGT1A6 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13312-NF from Sino Biological Species Human

Human UGT1A6 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13312-NM from Sino Biological Species Human

Human UGT1A6 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13312-CF from Sino Biological Species Human

Human UGT1A6 Gene ORF cDNA clone expression plasmid, N-His tag - HG13312-NH from Sino Biological Species Human

Human UGT1A6 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13312-CM from Sino Biological Species Human

Human UGT1A6 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13312-NY from Sino Biological Species Human

Human UGT1A6 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13312-ACR from Sino Biological Species Human

Human UGT1A6 Gene ORF cDNA clone expression plasmid, C-His tag - HG13312-CH from Sino Biological Species Human

Human UGT1A6 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13312-ACG from Sino Biological Species Human

Human UGT1A6 Gene ORF cDNA clone expression plasmid - HG13312-UT from Sino Biological Species Human

Human UGT1A6 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13312-CY from Sino Biological Species Human

Human UGT1A6 ORF clone (NM_001072.3) - CDCB159995 from Creative biogene Species Human

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