UGT1A6

Gene Symbol UGT1A6
Entrez Gene 54578
Alt Symbol GNT1, HLUGP, HLUGP1, UDPGT, UDPGT 1-6, UGT1, UGT1A6S, UGT1F
Species Human
Gene Type protein-coding
Description UDP glucuronosyltransferase 1 family, polypeptide A6
Other Description UDP glycosyltransferase 1 family, polypeptide A6|UDP-glucuronosyltransferase 1 family polypeptide A6s|UDP-glucuronosyltransferase 1-6|UDP-glucuronosyltransferase 1-F|UDP-glucuronosyltransferase 1A6|UGT-1F|UGT1*6|UGT1-06|UGT1.6|phenol-metabolizing UDP-glucuronosyltransferase
Swissprots P19224 A6NKK6 Q96TE7 B8K289
Accessions AAA61247 AAB87411 AAC41717 AAG30420 EAW71055 P19224 AY435141 AAR95642 BC011409 BC019861 AAH19861 BE463503 BM688740 BM924331 DB014621 DQ364250 ABC96774 J04093 AAA61251 NM_001072 NP_001063 NM_205862 NP_995584
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 3 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity). {ECO:0000250}.
Subcellular Location Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in skin. Isoforms 1 and 3 are expressed in kidney and liver. Isoform 1 but not isoform 2 is expressed in colon, esophagus and small intestine. {ECO:0000269|PubMed:1339448, ECO:0000269|PubMed:18004212}.
Top Pathways Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450

UGT1A6 CRISPR/Cas9 KO Plasmid (h) - sc-407961 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A6 HDR Plasmid (h) - sc-407961-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A6 Double Nickase Plasmid (h) - sc-407961-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A6 Double Nickase Plasmid (h2) - sc-407961-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A6 CRISPR Activation Plasmid (h) - sc-407961-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A6 CRISPR Activation Plasmid (h2) - sc-407961-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A6 Lentiviral Activation Particles (h) - sc-407961-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A6 Lentiviral Activation Particles (h2) - sc-407961-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A6 siRNA (h) - sc-44474 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UGT1A6 shRNA Plasmid (h) - sc-44474-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UGT1A6 shRNA (h) Lentiviral Particles - sc-44474-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UGT1A6 RNAi - H00054578-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN22461 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22461 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

UGT1A6 siRNA (Human) - CRJ0143 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UGT1A6 RNAi - H00054578-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

UGT1A6 - MBS8210995 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human UGT1A6 siRNA - orb270644 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UGT1A6 shRNA Plasmid (Human) - CHJ0143 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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