UGT1A6

Gene Symbol UGT1A6
Entrez Gene 54578
Alt Symbol GNT1, HLUGP, HLUGP1, UDPGT, UDPGT 1-6, UGT1, UGT1A6S, UGT1F
Species Human
Gene Type protein-coding
Description UDP glucuronosyltransferase 1 family, polypeptide A6
Other Description UDP glycosyltransferase 1 family, polypeptide A6|UDP-glucuronosyltransferase 1 family polypeptide A6s|UDP-glucuronosyltransferase 1-6|UDP-glucuronosyltransferase 1-F|UDP-glucuronosyltransferase 1A6|UGT-1F|UGT1*6|UGT1-06|UGT1.6|phenol-metabolizing UDP-glucuronosyltransferase
Swissprots P19224 A6NKK6 Q96TE7 B8K289
Accessions AAA61247 AAB87411 AAC41717 AAG30420 EAW71055 P19224 AY435141 AAR95642 BC011409 BC019861 AAH19861 BE463503 BM688740 BM924331 DB014621 DQ364250 ABC96774 J04093 AAA61251 NM_001072 NP_001063 NM_205862 NP_995584
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 3 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity). {ECO:0000250}.
Subcellular Location Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in skin. Isoforms 1 and 3 are expressed in kidney and liver. Isoform 1 but not isoform 2 is expressed in colon, esophagus and small intestine. {ECO:0000269|PubMed:1339448, ECO:0000269|PubMed:18004212}.
Top Pathways Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450

UGT1A6 (F-18) - sc-27432 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UGT1A6 (F-18): sc-27432. Western blot analysis of UGT1A6 expression in MOLT-4 (A), K-562 (B), HeLa (C) and Jurkat (D) whole cell lysates.

UGT1A6 (H-96) - sc-366831 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
UGT1A6 (H-96): sc-366831. Western blot analysis of UGT1A6 expression in Hep G2 (A) and HeLa (B) whole cell lysates.

UGT1A6 (P-16) - sc-27431 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UGT1A6 (P-16): sc-27431. Western blot analysis of UGT1A6 expression in non-transfected 293T: sc-117752 (A), human UGT1A6 transfected 293T: sc-113992 (B) and A-431 (C) whole cell lysates.

Anti-UGT1A6 antibody - ab97646 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-UGT1A6 antibody (ab97646) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-UGT1A6 antibody [EPR11067(B)] - ab155998 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11067(B)
All lanes : Anti-UGT1A6 antibody [EPR11067(B)] (ab155998) at 1/1000 dilutionLane 1 : Caco-2 cell lysateLane 2 : A431 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-UGT1A6 antibody [EPR11068] - ab157476 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11068
All lanes : Anti-UGT1A6 antibody [EPR11068] (ab157476) at 1/1000 dilutionLane 1 : Caco-2 cell lysateLane 2 : Fetal liver lysateLane 3 : A431 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-UGT1A6 Antibody - LS-C109532 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: A431. B: H1299. 7.5% SDS PAGE. UGT1A6 antibody diluted at 1:1000.

Anti-UGT1A6 Antibody (C-Terminus) - LS-C80423 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

UGT1A6 Antibody - NBP1-33743 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UGT1A6 Antibody [NBP1-33743] - A. 50 ug mouse liver lysate/extract 7.5 % SDS-PAGE. Dilution: 1:500

UGT1A6 Antibody - NBP1-69707 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UGT1A6 Antibody [NBP1-69707] - This Anti-UGT1A6 antibody was used in Western Blot of 293T tissue lysate at a concentration of 1ug/ml.

UGT1A6 Antibody - H00054578-B01 from Novus Biologicals

Host Mouse
Clonality Polyclonal
Western Blot: UGT1A6 Antibody [H00054578-B01] - analysis of UGT1A6 expression in transfected 293T cell line by UGT1A6 MaxPab polyclonal antibody. Lane 1: UGT1A6 transfected lysate (60.70 KDa). Lane 2: Non-transfected lysate.

UGT1A6 Antibody - H00054578-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

UGT1A6 Antibody (4A10) - H00054578-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A10
Sandwich ELISA: UGT1A6 Antibody (4A10) [H00054578-M03] - Detection limit for recombinant GST tagged UGT1A6 is 0.1 ng/ml as a capture antibody.

Anti-UGT1A6 antibody produced in rabbit - SAB2701153 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UGT1A6: <B>Cat. No. SAB2701153</B>: Immunohistochemical analysis of paraffin-embedded OV90 xenograft, using UGT1A6 antibody at 1:500 dilution.

Monoclonal Anti-UGT1A6 antibody produced in mouse - WH0054578M3 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A10

Anti-UGT1A6 antibody produced in rabbit - SAB1412845 from Sigma-Aldrich

Prices $391.50
Sizes 100 µg
Host Rabbit
<B>Immunoblotting</B><BR/>Anti-UGT1A6:<B>Cat. No. SAB1412845</B>: Antibody concentration: 0.1–5 μg/mL. Immunofluorescence band of ~60.7 kDa using UGT1A6 transfected 293T lysate.<BR/><B>Lane</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-UGT1A6 antibody produced in rabbit - SAB2102641 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-UGT1A6: <B>Cat. No.SAB2102641</B>: UGT1A6 in 293T cell lysate with UGT1A6 antibody at 1.0 μg/mL.

UGT1A6 Antibody (AMM10370A) - AMM10370A from Aviva Systems Biology

Prices $249.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8C6

UGT1A6 antibody - C-terminal region (ARP41458_P050) - ARP41458_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UGT1A6 antibody - orb74251 from Biorbyt

Prices $723.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Western Blot analysis of A:A431, B:H1299 whole cell lysate using UGT1A6 antibody

UGT1A6 antibody - 70R-21155 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

UGT1A6 antibody (OAGA01054) - OAGA01054 from Aviva Systems Biology

Prices $340.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UGT1A6 antibody - H00054578-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

UGT1A6 antibody - H00054578-D01P from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

UGT1A6 antibody - H00054578-M03 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A10
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