PREX1

Gene Symbol PREX1
Entrez Gene 57580
Alt Symbol P-REX1
Species Human
Gene Type protein-coding
Description phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Other Description phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein|ptdIns(3,4,5)-dependent Rac exchanger 1
Swissprots Q9UGQ4 Q9H4Q6 Q5JS96 E1P5X9 Q9BQH0 Q9P2D2 Q7Z2L9 Q5JS95 Q8TCU6 Q69YL2 Q9BX55
Accessions EAW75684 EAW75685 EAW75686 Q8TCU6 AB037836 BAA92653 AJ320261 CAC86401 AK090860 AL136579 CAB66514 AL832913 CAH10614 BC009948 BC053616 AAH53616 BC156402 AAI56403 XM_005260471 XP_005260528 XM_011528934 XP_011527236 XM_011528935 XP_011527237 NM_020820 NP_065871
Function Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
Subcellular Location Cytoplasm, cytosol. Cell membrane. Note=Mainly cytosolic. Some amount is apparently associated to the plasma membrane.
Tissue Specificity Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues.
Top Pathways Chemokine signaling pathway

Human PREX1 / P-REX1 ELISA Kit (Sandwich ELISA) - LS-F12400 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.156
Range 0.156-10 ng/ml

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, PREX1, Human, ELISA Kit - E3184h from ARP American Research Products

Category ELISA Kit
Prices $660.00
Sizes 96 t
Range 0.156-10 ng/mL

phosphatidylinositol-3, 4, 5-trisphosphate-dependent Rac exchange factor 1, ELISA Kit - MBS9318316 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse PREX1 / P-REX1 ELISA Kit (Custom ELISA) - LS-F19838 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

PREX1 - EKH4516 from Nordic BioSite

Sensitivity 0.094ng/ml
Range 0.156-10ng/ml

PREX1 ELISA Kit (Human) (OKEH01693) - OKEH01693 from Aviva Systems Biology

Category ELISA Kit
Prices $450.00
Sizes 96 wells
Sensitivity < 0.082 ng/mL
Range 0.156 - 10 ng/mL

Human PREX1 ELISA Kit - E028917 from Biobool

Category ELISA Kit
Sensitivity <0.094ng/ml

Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein ELISA Kit - EK4574 from Signalway Antibody

Category ELISA Kit
Prices $659.00
Sizes 1x96t
Sensitivity less than 29pg/mL
Range 78-5000 pg/mL

anti-PREX1 antibody - ARG64998 from Arigo Biolaboratories

Category ELISA Kit

Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (PREX1) ELISA Kit - AE26047HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t

Phosphatidylinositol 3, 4, 5-trisphosphate-dependent Rac exchanger 1 protein, ELISA Kit - MBS9428400 from MyBioSource

Category ELISA Kit
Prices $605.00
Sizes 96 tests
Sensitivity Less than 0.082ng/mL
Range 0.156-10 ng/mL

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, ELISA Kit - MBS2881090 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 0.156-10 ng/mL

Human PREX1 / P-REX1 ELISA Kit (Sandwich ELISA) - LS-F34214 from LifeSpan Bioscience

Category ELISA Kit
Sensitivity 0.094
Range 0.156-10 ng/ml
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