PREX1

Gene Symbol	PREX1
Entrez Gene	57580
Alt Symbol	P-REX1
Species	Human
Gene Type	protein-coding
Description	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Other Description	phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein|ptdIns(3,4,5)-dependent Rac exchanger 1
Swissprots	Q9UGQ4 Q9H4Q6 Q5JS96 E1P5X9 Q9BQH0 Q9P2D2 Q7Z2L9 Q5JS95 Q8TCU6 Q69YL2 Q9BX55
Accessions	EAW75684 EAW75685 EAW75686 Q8TCU6 AB037836 BAA92653 AJ320261 CAC86401 AK090860 AL136579 CAB66514 AL832913 CAH10614 BC009948 BC053616 AAH53616 BC156402 AAI56403 XM_005260471 XP_005260528 XM_011528934 XP_011527236 XM_011528935 XP_011527237 NM_020820 NP_065871
Function	Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
Subcellular Location	Cytoplasm, cytosol. Cell membrane. Note=Mainly cytosolic. Some amount is apparently associated to the plasma membrane.
Tissue Specificity	Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues.
Top Pathways	Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PREX1 / P-REX1 Antibody Blocking Peptide - LS-E1776 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PREX1 / P-REX1 Antibody Blocking Peptide - LS-E27140 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PREX1 / P-REX1 Antibody Blocking Peptide - LS-E10143 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PREX1-Antibody-C-term-Blocking-peptide - BP12575b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PREX1-Antibody-Center-Blocking-Peptide - BP9461c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PREX1 blocking peptide - GTX88346-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

PREX1 Peptide - AC21-1959-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PREX1 Peptide - 42-175P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein(PREX1) ,partial - CSB-YP848403HU CSB-EP848403HU CSB-BP848403HU CSB-MP848403HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (PREX1), partial, Recombinant Protein - MBS1309746 from MyBioSource Category Protein Prices $1,145.00, $1,145.00, $1,370.00, $1,370.00, $1,770.00, $1,770.00, $2,230.00, $2,230.00, $2,260.00, $3,490.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PREX1, Peptide - MBS426745 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

P-Rex1 Protein - NBP1-93590PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

PREX1 Peptide, Human - M34GP12371H from Creative Peptides Category Peptide Source Synthetic. Species Human

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