CISD2

Gene Symbol	CISD2
Entrez Gene	493856
Alt Symbol	ERIS, Miner1, NAF-1, WFS2, ZCD2
Species	Human
Gene Type	protein-coding
Description	CDGSH iron sulfur domain 2
Other Description	CDGSH iron-sulfur domain-containing protein 2|endoplasmic reticulum intermembrane small protein|mitoNEET-related 1 protein|nutrient-deprivation autophagy factor-1|zinc finger, CDGSH-type domain 2
Swissprots	Q7Z3D5 Q8N5K1
Accessions	EAX06148 EAX06149 Q8N5K1 AA424361 AI277147 AK292134 BAF84823 AM392809 CAL37687 AM393385 CAL38263 BC020831 BC032300 AAH32300 BX537971 CAD97935 DB351048 DB565768 DN993861 NM_001008388 NP_001008389
Function	Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy. {ECO:0000269|PubMed:17846994, ECO:0000269|PubMed:20010695}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein. Note=According to PubMed:20010695, it mainly localizes to the endoplasmic reticulum. However, experiments in mouse showed that it mainly localizes to the mitochondrion outer membrane.
Tissue Specificity	Testis, small intestine, kidney, lung, brain, heart, pancreas and platelets. {ECO:0000269|PubMed:17846994}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CISD2 cDNA Clone - orb142525 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human-CISD2-cDNA-Clone - DC06349 from Abgent, a WuXi AppTec company Prices $183.60 Sizes 10 µg Species Human Accession BC032300

CISD2 cDNA (ANA10244) - ANA10244 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC032300

CISD2 cDNA (ANA10245) - ANA10245 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC032300

CISD2 cDNA (ANA10516) - ANA10516 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC032300

CISD2 cDNA (ANA10517) - ANA10517 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC032300

CISD2 - MBS1274839 from MyBioSource

Human CISD2 ORF Clone(NM_001008388.4) - CDCL158904 from Creative Biomart Species Human Accession NM_001008388.4

Human CISD2 Gene ORF cDNA clone in cloning vector - HG14432-G from Sino Biological Species Human

Human CISD2 Gene ORF cDNA clone expression plasmid, C-His tag - HG14432-CH from Sino Biological Species Human

Human CISD2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14432-ACR from Sino Biological Species Human

Human CISD2 Gene ORF cDNA clone expression plasmid - HG14432-UT from Sino Biological Species Human

Human CISD2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14432-CY from Sino Biological Species Human

Human CISD2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14432-NF from Sino Biological Species Human

Human CISD2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14432-CF from Sino Biological Species Human

Human CISD2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14432-NM from Sino Biological Species Human

Human CISD2 Gene ORF cDNA clone expression plasmid, N-His tag - HG14432-NH from Sino Biological Species Human

Human CISD2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14432-CM from Sino Biological Species Human

Human CISD2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14432-NY from Sino Biological Species Human

Human CISD2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14432-ACG from Sino Biological Species Human

Human CISD2 ORF Clone (BC032300) - CDCS406356 from Creative biogene Species Human Accession Q8N5K1

Human CISD2 ORF clone (BC032300) - CDCB158944 from Creative biogene Species Human

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