CISD2

Gene Symbol	CISD2
Entrez Gene	493856
Alt Symbol	ERIS, Miner1, NAF-1, WFS2, ZCD2
Species	Human
Gene Type	protein-coding
Description	CDGSH iron sulfur domain 2
Other Description	CDGSH iron-sulfur domain-containing protein 2|endoplasmic reticulum intermembrane small protein|mitoNEET-related 1 protein|nutrient-deprivation autophagy factor-1|zinc finger, CDGSH-type domain 2
Swissprots	Q7Z3D5 Q8N5K1
Accessions	EAX06148 EAX06149 Q8N5K1 AA424361 AI277147 AK292134 BAF84823 AM392809 CAL37687 AM393385 CAL38263 BC020831 BC032300 AAH32300 BX537971 CAD97935 DB351048 DB565768 DN993861 NM_001008388 NP_001008389
Function	Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy. {ECO:0000269|PubMed:17846994, ECO:0000269|PubMed:20010695}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein. Note=According to PubMed:20010695, it mainly localizes to the endoplasmic reticulum. However, experiments in mouse showed that it mainly localizes to the mitochondrion outer membrane.
Tissue Specificity	Testis, small intestine, kidney, lung, brain, heart, pancreas and platelets. {ECO:0000269|PubMed:17846994}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CISD2 full length protein - ab166558 from Abcam Category Protein Source Wheat germ Species Human

NAF-1 / CISD2 Antibody Blocking Peptide - LS-E16369 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NAF-1 / CISD2 Antibody Blocking Peptide - LS-E31426 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CISD2 Recombinant Protein - H00493856-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CISD2 Protein Lysate (APL10244) - APL10244 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

CISD2 Protein Lysate (APL10245) - APL10245 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

CISD2 Protein Lysate (APL10516) - APL10516 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

CISD2 Protein Lysate (APL10517) - APL10517 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

CISD2 Blocking Peptide - 33R-9652 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CISD2 - H00493856-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CISD2 - H00493856-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CISD2 Peptide - 7301P from ProSci Category Peptide Species Human

CISD2 fusion protein - Ag18759 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

CISD2 fusion protein - Ag4172 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human CISD2, His-tagged - CISD2-11254H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human CDGSH iron-sulfur domain-containing protein 2(CISD2) - CSB-YP839803HU CSB-EP839803HU CSB-BP839803HU CSB-MP839803HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CISD2 (full length, N-term HIS tag) - TP760576 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

CDGSH iron-sulfur domain-containing protein 2 (CISD2), Recombinant Protein - MBS1374132 from MyBioSource Category Protein Prices $805.00, $805.00, $1,030.00, $1,030.00, $1,135.00, $1,135.00, $1,590.00, $1,590.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CISD2 Recombinant Protein Antigen - NBP1-84809PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CISD2 Protein Lysate - orb333419 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

CISD2 Peptide, Human - M34GP03184H from Creative Peptides Category Peptide Source Synthetic. Species Human

CISD2 Protein Lysate - orb333215 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

CISD2 Protein Lysate - orb333420 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

CISD2 Protein Lysate - orb333214 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

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